泌尿系结石并发代谢综合征与结石复发的关联性分析
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摘要
目的探讨泌尿系结石患者并发代谢综合征(MS)与结石复发问的相关性。方法对2013年6月-2016年6月收治的120例泌尿系结石患者资料进行分析,以是否并发MS分成MS组(28例)和非MS组(92例),随访24～62个月,对比两组间结石复发率及复发时间,以多元Cox回归分析MS与泌尿系结石复发之问是否有相关性。结果 MS组患者结石复发率显著高于非MS组、MS组复发时间显著小于非MS组,差异均有统计学意义(P <0. 05)。经多元Cox回归分析提示,性别、年龄、初诊复发性结石与患者结石复发无相关性,而并发MS与患者结石复发存在明显相关性(HR=1. 939,95%CI:1. 227～2. 980,P <0. 05)。结论 MS是泌尿系结石患者结石复发的一个独立危险因素,对于泌尿系结石患者并发MS时,在预防结石复发同时应积极治疗MS。
Objective To investigate the correlation between urinary stone patients complicated with metabolic syndrome( MS) and stone recurrence. Methods In June 2013 to June 2016 treated 120 cases of urinary calculi patients data were analyzed retrospectively,to whether concurrent MS into MS group( 28 cases) and non MS group( 92 cases),24 ～ 62 months follow-up,comparative and calculi recurrence rate and time of recurrence between the two groups,with multivariate Cox regression analysis of MS and asked whether there is a correlation between urinary calculi recurrence. Results the recurrence rate of stones in the MS group was significantly higher than that in the non-ms group,and the recurrence time in the MS group was significantly lower than that in the non-ms group,with statistically significant differences( P < 0. 05). Multivariate Cox regression analysis indicated that there was no correlation between gender,age,newly diagnosed recurrent stones and the recurrence of stones in patients,while there was a significant correlation between MS and the recurrence of stones in patients( HR = 1. 939,95% CI: 1. 227 ～ 2. 980,P < 0. 05).Conclusions MS is an independent risk factor for stone recurrence in patients with urinary calculi. For patients with urinary calculi complicated with MS,MS should be actively treated while preventing stone recurrence.
Objective To investigate the correlation between urinary stone patients complicated with metabolic syndrome( MS) and stone recurrence. Methods In June 2013 to June 2016 treated 120 cases of urinary calculi patients data were analyzed retrospectively,to whether concurrent MS into MS group( 28 cases) and non MS group( 92 cases),24 ～ 62 months follow-up,comparative and calculi recurrence rate and time of recurrence between the two groups,with multivariate Cox regression analysis of MS and asked whether there is a correlation between urinary calculi recurrence. Results the recurrence rate of stones in the MS group was significantly higher than that in the non-ms group,and the recurrence time in the MS group was significantly lower than that in the non-ms group,with statistically significant differences( P < 0. 05). Multivariate Cox regression analysis indicated that there was no correlation between gender,age,newly diagnosed recurrent stones and the recurrence of stones in patients,while there was a significant correlation between MS and the recurrence of stones in patients( HR = 1. 939,95% CI: 1. 227 ～ 2. 980,P < 0. 05).Conclusions MS is an independent risk factor for stone recurrence in patients with urinary calculi. For patients with urinary calculi complicated with MS,MS should be actively treated while preventing stone recurrence.
引文
[1]谌琦,李月红,李建兴.泌尿系结石与代谢性疾病的相关性[J].现代泌尿外科杂志,2018,23(8):633-635.
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[2]陈星,郭剑明,王国民,等.代谢综合征与泌尿系结石尿液危险因素的相关性[J].复旦学报(医学版),2015,42(5):596-600.
[3]李慧娟.代谢综合征及其组分与泌尿系结石相关性的分析研究[D].山东大学,2014:1-0.
[4]张立峰,方志辉,靳勇,等.影响泌尿系结石的多因素研究[J].黑龙江医药,2015,3(1):170-172.
[5]周璠娅.泌尿系结石患者发病危险因素调查研究[J].河北医学,2016,22(3):458-461.
[6]王刚,何海宝,王涛.泌尿系结石并发代谢综合征与结石复发的关联性分析[J].中国医师杂志,2018,20(3):458-460.