2016年大理州健康人群麻疹抗体水平监测结果分析

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英文篇名：To analyze the monitoring results of the antibody levels of Measles in healthy people in Dali prefecture in 2016 作者：段飞云 英文作者：DUAN Fei-yun;Dali prefecture Centers for Disease Control and Prevention; 关键词：麻疹抗体 ; 阳性率 ; 几何平均浓度 英文关键词：measles antibody;;positive rate;;Geometric Mean Concentration 中文刊名：JBJK 英文刊名：Journal of Diseases Monitor & Control 机构：大理州疾病预防控制中心; 出版日期：2017-08-15 出版单位：疾病监测与控制 年：2017 期：v.11;No.125 语种：中文; 页：JBJK201708002 页数：3 CN：08 ISSN：15-1350/R 分类号：6-8

摘要

目的了解大理州健康人群麻疹抗体水平,为制定免疫规划策略和防治措施提供科学依据。方法采用酶联免疫吸附试验(ELISA)对3 858名健康人群麻疹Ig G抗体进行检测,按照不同地区、年龄、民族、性别进行分组,比较不同组别人群的麻疹抗体阳性率和几何平均浓度(Geometric Mean Concentration,GMC)。结果大理州麻疹抗体阳性率为89.5%,麻疹抗体几何平均浓度(GMC)为904.31ml U/m L。各地区、年龄组、民族麻疹抗体阳性率均有统计学差异(χ2值分别为99.69、88.48、38.24,P值均﹤0.05),性别间抗体阳性率无统计学差异(χ2=2.32,P﹥0.05)。不同地区、年龄、民族、性别间的麻疹抗体GMC均有统计学差异(F值分别为17.85、38.45、7.12、4.74,P值均﹤0.05)。结论大理州健康人群麻疹抗体处于较高水平,发生大规模暴发流行概率极低,回族和25~34岁仍然是麻疹的高危人群,应加强对这部分人群的监测及查漏补种。
        Objectives To understand the antibody levels of Measles in healthy people in Dali prefecture. To provide scientific basis for immune planning strategy and prevention and control measures. Methods To detect the antibody levels of Measles by Enzyme-linked immune sorbent assay(ELISA). And to group the sample by counties, ages, nationalities and genders. To make comparison for positive rate and Geometric Mean Concentration(GMC) of measles antibody according to different groups people. Results The positive rate of measles antibody is 89.5%. And the GMC is 904.31 ml U/m L. The positive rate of measles antibody was significantly different in different counties, age groups and nationalities(χ2 values respectively are 99.69、88.48、38.24, P values are all ﹤0.05). There was no significant difference between genders(χ2=2.32, P﹥0.05). The GMC was significantly different in different counties, age groups, nationalities and genders(F values respectively are 17.85、38.45、7.12、4.74, P values are all ﹤0.05). Conclusions The positive rate of Measles Ig G was at a high level in Dali prefecture. It's extremely low for Large-scale outbreak of measles. The Hui nationality and 25 to 34 years old both are the high-risk population for Measles. So we should strengthen monitoring and timely vaccination of Measles for the population.

引文

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