中药离子导入联合关节腔注射益赛普治疗类风湿性关节炎患者的临床疗效分析

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英文篇名：Clinical Analysis of Traditional Chinese Medicine Iontophoresis Combined with Intra-articular Injection of Yisaipu in the Treatment of Patients with Rheumatoid Arthritis 作者：柴丽娟 英文作者：CHAI Li-juan;Department of Traditional Chinese Medicine, Gucheng County Hospital; 关键词：类风湿性关节炎 ; 中药离子导入 ; 益赛普 英文关键词：Rheumatoid arthritis;;Chinese medicine iontophoresis;;Yisaipu 中文刊名：HZZZ 英文刊名：China & Foreign Medical Treatment 机构：河北省故城县医院中医内科; 出版日期：2019-02-01 出版单位：中外医疗 年：2019 期：v.38 语种：中文; 页：HZZZ201904032 页数：4 CN：04 ISSN：11-5625/R 分类号：102-105

摘要

目的探究中药离子导入联合益赛普治疗类风湿性关节炎患者的临床疗效。方法研究对象方便选自2015年1月—2017年1月该院收治的90例类风混关节炎患者。根据随机数字表发随机分为两组。益赛普组患者接受关节腔注射(益赛普25 mg每月1次,共3次)。中药离子导入组患者在益赛普治疗的基础上加用采用中药离子导入。3个疗程后评价两组患者Lysholm膝关节评分、临床疗效和临床治疗的满意度。结果接受不同治疗方案3个疗程后,益赛普组Lysholm评分上升至(82.5±7.6)分,但中药离子导入组患者接受治疗后Lysholm评分上升幅度更高,且大于益赛普组(P<0.05);单纯益赛普组治愈21例,好转15例,未愈9例,总有效率为80.0%;中药离子导入联合益赛普组治愈,治愈30例,好转13例,未愈2例,总有效率为95.6%(P<0.05);中药离子导入组患者对临床治疗满意人数多于益赛普组(P<0.05)。结论中药离子导入联合关节注射益赛普可明显缓解患者疼痛,且能减轻患者经济负担,有助于膝关节功能的恢复,加速疾病转归,使患者获得更加满意的临床治疗
        Objective To investigate the clinical efficacy of traditional Chinese medicine iontophoresis combined with Yisaipu in the treatment of patients with rheumatoid arthritis. Methods The study subjects were convenient selected from 90 patients with rheumatoid arthritis from January 2015 to January 2017. According to the random number table, they are randomly divided into two groups. Patients in the Yisaipu group received intra-articular injection(Yesaipu 25 mg once a month for 3 times). The Chinese medicine iontophoresis group was added with the traditional Chinese medicine iontophoresis based on the treatment of Yisaipu. After 3 courses of treatment, the Lysholm knee score, clinical efficacy and clinical treatment satisfaction were evaluated. Results After 3 courses of different treatment regimens, the Lysholm score of the Yisaipu group increased to(82.5 ±7.6)points, but the Lysholm score increased more in the Chinese medicine iontophoresis group than in the Yisaipu group(t =0.108, P <0.05); 21 cases were cured in Yisaipu group, 15 cases were improved, 9 cases were unhealed, the total effective rate was 80.0%; Chinese medicine iontophoresis combined with Yisaipu group was cured, 30 cases were cured, 13 cases were improved, and 2 cases were not cured. The total effective rate was 95.6%(P<0.05); the patients in the iontophoresis group of Chinese medicine were more satisfied with the clinical treatment than the Yisaipu group(P<0.05). Conclusion Chinese medicine iontophoresis combined with joint injection of Yisaipu can significantly alleviate the pain of patients, and can reduce the economic burden of patients, help the recovery of knee joint function, accelerate the disease outcome, and enable patients to obtain more satisfactory clinical treatment.

引文

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