2012—2017年西充县人民医院药品不良反应报告分析
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摘要
目的分析西充县人民医院2012—2017年药品不良反应(ADR)发生的规律和特点,为进一步加强该院ADR监测水平和临床安全用药提供参考。方法对西充县人民医院2012—2017年ADR报告进行整理汇总,对患者性别组成、年龄分布、给药途径,ADR类型以及药品种类等进行统计分析。结果 2012—2017年ADR报告例数逐年上升,共纳入843例ADR报告进行分析,其中男性占50.42%,女性占49.58%;老年患者ADR发生率占比最高;抗感染药物类、消化系统类药物、心血管系统类药物以及电解质和营养药ADR发生率较高,但抗感染药物ADR发生风险呈现逐年下降的趋势。结论近6年来西充县人民医院ADR报告质量逐年提升,但仍需持续提高药品管理水平,规范医疗用药的合理性和安全性,减少患者用药的不适感和安全风险,以期促进该院不良反应监测工作上升到一个新台阶。
Objective To analyze the regularity and characteristics of the adverse drug reaction(ADR) in Xichong County People's Hospital from 2012 to 2017, and provide reference for further strengthening the ADR monitoring level and clinical safety medication in our hospital. Methods The ADR reports of this hospital from 2012 to 2017 was compiled and summarized, and the patient's gender composition, age distribution, administration route, ADR type and drug type were statistically analyzed. Results The number of ADR reports in 2012—2017 increased year by year. A total of 843 ADR reports were included for analysis. Among them, 50.42%were men and 49.58% were women. The incidence of ADR was the highest in elderly patients. The ADR incidence of anti-infective drugs, digestive system drugs, cardiovascular system drugs and electrolytes and nutrients ADR was higher, but the risk of antiinfective drugs ADR was in a decreasing trend year by year. Conclusion In the past six years, the quality of ADR reports in Xichong County People's Hospital has increased by yeard, but it is still necessary to continuously improve the level of drug management, standardize the rationality and safety of medical drugs, reduce the discomfort and safety risks of patients, in order to promote the monitoring of adverse reactions in this hospital to a new step.
Objective To analyze the regularity and characteristics of the adverse drug reaction(ADR) in Xichong County People's Hospital from 2012 to 2017, and provide reference for further strengthening the ADR monitoring level and clinical safety medication in our hospital. Methods The ADR reports of this hospital from 2012 to 2017 was compiled and summarized, and the patient's gender composition, age distribution, administration route, ADR type and drug type were statistically analyzed. Results The number of ADR reports in 2012—2017 increased year by year. A total of 843 ADR reports were included for analysis. Among them, 50.42%were men and 49.58% were women. The incidence of ADR was the highest in elderly patients. The ADR incidence of anti-infective drugs, digestive system drugs, cardiovascular system drugs and electrolytes and nutrients ADR was higher, but the risk of antiinfective drugs ADR was in a decreasing trend year by year. Conclusion In the past six years, the quality of ADR reports in Xichong County People's Hospital has increased by yeard, but it is still necessary to continuously improve the level of drug management, standardize the rationality and safety of medical drugs, reduce the discomfort and safety risks of patients, in order to promote the monitoring of adverse reactions in this hospital to a new step.
引文
[1]王丹,程刚.药品不良反应监测数据年度趋势分析[J].药物流行病学杂志, 2013, 22(5):238-241.
[2]国家食品药品监督管理总局.国家药品不良反应监测年度报告(2016年)[EB/OL].(2017-04-28)[2018-10-23].http://samr.cfda.gov.cn/WS01/CL0844/172167.html.
[3]熊代琴,李桂荣,阳莹,等.某院2009例药品不良反应报告回顾性分析[J].中国医院药学杂志, 2017, 37(17):1753-1759.
[4]李薇,沈剑,侯宏伟,等. 2011—2016年鄂州市中心医院抗菌药不良反应分析[J].药物评价研究, 2017, 40(5):700-705.
[5]国家食品药品监督管理总局.药品不良反应报告和监测管理办法[EB/OL].(2011-05-04)[2018-10-23]. http://www.sda.gov.cn/WS01/CL0053/62621.html.
[6]孙定人,齐平,靳颖华,等.药物不良反应[M].北京:人民卫生出版社, 2003:55.
[7]左鼎,车佳莹,谢娟,等.某院2014-2016年947例药品不良反应回顾性分析[J].现代医药卫生, 2018, 34(13):2051-2054.
[8]刘玉,魏威,宋勇波.湖北省3家三级综合医院药物不良反应报告的回顾性分析[J].中国医药导报, 2018, 34(13):174-177.
[9]张彦昭,文占权,刘传绪,等. 2013—2016年国家药品不良反应监测年度报告统计分析[J]. 2017, 26(11):763-765.
[10]余文浩,李玉珍,曾繁涛,等.我院433例药品不良反应报告分析[J].中国药房, 2016, 27(26):3640-3643.
[11]刘平,徐国防,刘长缨,等.我院368例药品不良反应报告分析[J].中国药房, 2015, 26(35):4955-4957.
[12]周甜甜,王录.我院285例药品不良反应报告分析[J].中国现代医药杂志, 2018, 20(9):102-104.
[13]张莉,周鸣. 416例药品不良反应报告回顾性分析[J].中国药业, 2016, 25(1):90-92.
[14]陈奕伸,万正兰,卓飞霞,等. 236例药品不良反应报告分析[J].中国药房, 2014, 25(14):1307-1310.
[15]王丽,何琴,张松,等.我院322例药品不良反应报告回顾性分析[J].药物流行病学杂志, 2015, 24(6):364-367.
[2]国家食品药品监督管理总局.国家药品不良反应监测年度报告(2016年)[EB/OL].(2017-04-28)[2018-10-23].http://samr.cfda.gov.cn/WS01/CL0844/172167.html.
[3]熊代琴,李桂荣,阳莹,等.某院2009例药品不良反应报告回顾性分析[J].中国医院药学杂志, 2017, 37(17):1753-1759.
[4]李薇,沈剑,侯宏伟,等. 2011—2016年鄂州市中心医院抗菌药不良反应分析[J].药物评价研究, 2017, 40(5):700-705.
[5]国家食品药品监督管理总局.药品不良反应报告和监测管理办法[EB/OL].(2011-05-04)[2018-10-23]. http://www.sda.gov.cn/WS01/CL0053/62621.html.
[6]孙定人,齐平,靳颖华,等.药物不良反应[M].北京:人民卫生出版社, 2003:55.
[7]左鼎,车佳莹,谢娟,等.某院2014-2016年947例药品不良反应回顾性分析[J].现代医药卫生, 2018, 34(13):2051-2054.
[8]刘玉,魏威,宋勇波.湖北省3家三级综合医院药物不良反应报告的回顾性分析[J].中国医药导报, 2018, 34(13):174-177.
[9]张彦昭,文占权,刘传绪,等. 2013—2016年国家药品不良反应监测年度报告统计分析[J]. 2017, 26(11):763-765.
[10]余文浩,李玉珍,曾繁涛,等.我院433例药品不良反应报告分析[J].中国药房, 2016, 27(26):3640-3643.
[11]刘平,徐国防,刘长缨,等.我院368例药品不良反应报告分析[J].中国药房, 2015, 26(35):4955-4957.
[12]周甜甜,王录.我院285例药品不良反应报告分析[J].中国现代医药杂志, 2018, 20(9):102-104.
[13]张莉,周鸣. 416例药品不良反应报告回顾性分析[J].中国药业, 2016, 25(1):90-92.
[14]陈奕伸,万正兰,卓飞霞,等. 236例药品不良反应报告分析[J].中国药房, 2014, 25(14):1307-1310.
[15]王丽,何琴,张松,等.我院322例药品不良反应报告回顾性分析[J].药物流行病学杂志, 2015, 24(6):364-367.