复方甘草酸苷在慢性特发性荨麻疹治疗中的实践研究
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摘要
目的探讨了复方甘草酸苷在慢性特发性荨麻疹治疗中的实践效果。方法选取2018年3月～2019年2月在本院接受治疗的慢性特发性荨麻疹患者68例,按照随机数表法将患者分为两组,对照组和观察组患者各34例,对照组患者采取咪唑斯汀进行治疗,观察组患者采取复方甘草酸苷,对比两组患者的治疗效果。结果观察组患者的治疗有效率为97.05%明显高于对照组的82.35%,差异有统计学意义(P<0.05),观察组并发症发生率、复发率低于对照组,差异有统计学意义(x2=4.220、4.909,P=0.039、0.026),观察组生活质量指数DLQL评分明显高于对照组的,差异有统计学意义(P<0.05)。结论复方甘草酸苷在慢性特发性荨麻疹治疗中能够有效缓解患者临床症状,取得较为显著的治疗效果。
Objective To investigate the clinical effect of Compound Glycyrrhizin in the treatment of chronic idiopathic urticaria. Methods 68 patients with chronic idiopathic urticaria who were treated in our hospital from March 2018 to February 2019 were selected and divided into two groups according to the random number table method. 34 patients in the control group and 34 patients in the observation group were treated with mizolastine,while 34 patients in the observation group were treated with compound glycyrrhizin. Results The effective rate of treatment in the observation group was 97.05% higher than 82.35% in the control group(P<0.05). The incidence of complications and recurrence in the observation group were lower than those in the control group(x~2=4.220, 4.909,P=0.039, 0.026). The DLQL score in the observation group was significantly higher than that in the control group(P<0.05). Conclusion Compound glycyrrhizin can effectively relieve the clinical symptoms of patients with chronic idiopathic urticaria and achieve a more significant therapeutic effect.
Objective To investigate the clinical effect of Compound Glycyrrhizin in the treatment of chronic idiopathic urticaria. Methods 68 patients with chronic idiopathic urticaria who were treated in our hospital from March 2018 to February 2019 were selected and divided into two groups according to the random number table method. 34 patients in the control group and 34 patients in the observation group were treated with mizolastine,while 34 patients in the observation group were treated with compound glycyrrhizin. Results The effective rate of treatment in the observation group was 97.05% higher than 82.35% in the control group(P<0.05). The incidence of complications and recurrence in the observation group were lower than those in the control group(x~2=4.220, 4.909,P=0.039, 0.026). The DLQL score in the observation group was significantly higher than that in the control group(P<0.05). Conclusion Compound glycyrrhizin can effectively relieve the clinical symptoms of patients with chronic idiopathic urticaria and achieve a more significant therapeutic effect.
引文
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[8]韩强.富马酸卢帕他定、依巴斯汀联合复方甘草酸苷治疗慢性荨麻疹的疗效观察[J].皮肤病与性病,2018,40(5):684-685.
[9]兰建平.复方甘草酸苷联合枸地氯雷他啶片治疗慢性荨麻疹的疗效观察[J].皮肤病与性病,2018,40(5):690-691.
[10]袁六六.复方甘草酸苷注射液联合西药治疗荨麻疹的临床疗效研究[J].皮肤病与性病,2018,40(5):693-694.
[2]王媛.咪唑斯汀联合复方甘草酸苷治疗慢性特发性荨麻疹的效果探析[J].当代医药论丛,2017,15(1):103-104.
[3]谭李萍.复方甘草酸苷注射液治疗慢性特发性荨麻疹的临床疗效观察[J].医药前沿,2017,7(3):22-23.
[4]赵以会.咪唑斯汀结合复方甘草酸苷治疗慢性特发性荨麻疹疗效观察[J].中国继续医学教育,2018,10(12):133-135.
[5]董晓磊.复方甘草酸苷片冶疗慢性荨麻疹的临床价值分析[J].临床医药文献电子杂志,2017,4(70):13819.
[6]王娜.复方甘草酸苷联合咪唑斯汀治疗慢性荨麻疹疗效分析[J].皮肤病与性病,2018,169(2):131-132.
[7]盛国华,孙爱猛,尹梅丹,等.地氯雷他定与复方甘草酸苷联用对患者慢性荨麻疹的临床疗效及其对免疫功能改善的影响[J].抗感染药学,2018,15(9):1603-1605.
[8]韩强.富马酸卢帕他定、依巴斯汀联合复方甘草酸苷治疗慢性荨麻疹的疗效观察[J].皮肤病与性病,2018,40(5):684-685.
[9]兰建平.复方甘草酸苷联合枸地氯雷他啶片治疗慢性荨麻疹的疗效观察[J].皮肤病与性病,2018,40(5):690-691.
[10]袁六六.复方甘草酸苷注射液联合西药治疗荨麻疹的临床疗效研究[J].皮肤病与性病,2018,40(5):693-694.