微创手术联合置管吸引手术治疗老年脑出血对炎性因子水平及患者生活质量的改善效果
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摘要
目的:探讨微创手术联合置管吸引手术治疗老年脑出血的临床疗效,及对患者血清炎性因子水平、生活质量的影响。方法:将本院收治的84例老年脑出血患者按照随机数字表法进行分组:对照组(42例)实施药物治疗,观察组(42例)在药物治疗基础上行微创置管吸引手术。检测两组治疗前后的炎性因子(IL-6、TNF-α、hs-CRP)水平,对比神经功能、生活质量评分变化。结果:两组治疗后的TNF-α、IL-6、hs-CRP水平均显著低于治疗前(P<0.05),观察组各项指标水平明显更低(P<0.05)。观察组与对照组的治疗总有效率比较,差异有统计学意义(80.95%VS 57.14%,P<0.05)。在生活质量评分方面,观察组治疗后各维度的生活质量评分均显著高于对照组(P<0.05)。结论:老年脑出血患者行微创手术联合置管吸引手术有确切疗效,手术能明显降低炎性因子水平,促进神经功能恢复,改善患者预后及生活质量。
Objective:To investigate the clinical efficacy of minimally invasive surgery combined with catheter aspiration for the treatment of senile cerebral hemorrhage,and its effect on serum inflammatory factor levels and quality of life.Methods:84 elderly patients with cerebral hemorrhage admitted to our hospital were divided into two groups according to the random number table method: the control group(42 cases) received drug treatment, and the observation group(42 cases) underwent minimally invasive catheter aspiration surgery on the basis of drug treatment.The levels of inflammatory factors(IL-6,TNF-α,hs-CRP) before and after treatment were measured, and the changes in neurological function and quality of life scores were compared.Results:The levels of TNF-α,IL-6 and hs-CRP in the two groups were significantly lower than those before treatment, and the differences between the two groups were statistically significant. The levels of the indicators in the observation group were significantly lower(P<0.05).The total effective rate of the observation group and the control group was statistically significant(90.95% VS 57.14%,P<0.05). In terms of quality of life scores, the quality of life scores of the observation groups were significantly higher than those of the control group(P<0.05).Conclusion:Minimally invasive surgery combined with catheter aspiration surgery in elderly patients with cerebral hemorrhage has a definite curative effect.Surgery can significantly reduce the level of inflammatory factors,promote the recovery of neurological function,and improve the prognosis and quality of life of patients.
Objective:To investigate the clinical efficacy of minimally invasive surgery combined with catheter aspiration for the treatment of senile cerebral hemorrhage,and its effect on serum inflammatory factor levels and quality of life.Methods:84 elderly patients with cerebral hemorrhage admitted to our hospital were divided into two groups according to the random number table method: the control group(42 cases) received drug treatment, and the observation group(42 cases) underwent minimally invasive catheter aspiration surgery on the basis of drug treatment.The levels of inflammatory factors(IL-6,TNF-α,hs-CRP) before and after treatment were measured, and the changes in neurological function and quality of life scores were compared.Results:The levels of TNF-α,IL-6 and hs-CRP in the two groups were significantly lower than those before treatment, and the differences between the two groups were statistically significant. The levels of the indicators in the observation group were significantly lower(P<0.05).The total effective rate of the observation group and the control group was statistically significant(90.95% VS 57.14%,P<0.05). In terms of quality of life scores, the quality of life scores of the observation groups were significantly higher than those of the control group(P<0.05).Conclusion:Minimally invasive surgery combined with catheter aspiration surgery in elderly patients with cerebral hemorrhage has a definite curative effect.Surgery can significantly reduce the level of inflammatory factors,promote the recovery of neurological function,and improve the prognosis and quality of life of patients.
引文
[1] 张兆勇.比较微创定向置软管吸引术、开颅脑内血肿清除术对脑出血的治疗价值[J].影像研究与医学应用,2018,2(15):200-201.
[2] 王秦川.探讨微创置管吸引术对脑出血患者神经、认知功能的影响[J].临床医药文献电子杂志,2018,5(35):56-57.
[3] 徐春林,冯石萍.微创联合置管吸引手术对脑出血患者生活质量的影响[J].实用临床医药杂志,2018,22(5):121-124.
[4] 张华平,陈晓雷,周定标.高血压脑出血的外科治疗进展[J].长江大学学报:自科版,2017,14(20):80-85,109.
[5] 葛新,陈晓雷,孙吉庆,等.神经内镜微创手术与开颅血肿清除术治疗高血压脑出血疗效比较[J].中国神经精神疾病杂志,2016,42(10):605-608.
[6] 耿建国,张玉勇.微创手术对中等量高血压性基底节区脑出血患者神经功能的影响[J].中国临床研究,2016,29(10):1366-1368.
[7] 李楠.高血压脑出血神经内镜微创手术与开颅血肿清除术的临床比较分析[J].中国医学工程,2016,24(9):33.
[8] 张盼盼.微创手术联合置管吸引手术对老年脑出血患者愈合影响探析[J].中国老年保健医学,2016,14(3):68.
[9] 张强.传统开颅手术与显微镜下微创手术治疗基底节区高血压脑出血的临床疗效比较[J].医学综述,2016,22(6):1246-1248.
[10] 杜新亮,武强.微创定向置软管吸引术与开颅脑内血肿清除术治疗中度脑出血疗效分析[J].航空航天医学杂志,2015,26(9):1102-1103.
[2] 王秦川.探讨微创置管吸引术对脑出血患者神经、认知功能的影响[J].临床医药文献电子杂志,2018,5(35):56-57.
[3] 徐春林,冯石萍.微创联合置管吸引手术对脑出血患者生活质量的影响[J].实用临床医药杂志,2018,22(5):121-124.
[4] 张华平,陈晓雷,周定标.高血压脑出血的外科治疗进展[J].长江大学学报:自科版,2017,14(20):80-85,109.
[5] 葛新,陈晓雷,孙吉庆,等.神经内镜微创手术与开颅血肿清除术治疗高血压脑出血疗效比较[J].中国神经精神疾病杂志,2016,42(10):605-608.
[6] 耿建国,张玉勇.微创手术对中等量高血压性基底节区脑出血患者神经功能的影响[J].中国临床研究,2016,29(10):1366-1368.
[7] 李楠.高血压脑出血神经内镜微创手术与开颅血肿清除术的临床比较分析[J].中国医学工程,2016,24(9):33.
[8] 张盼盼.微创手术联合置管吸引手术对老年脑出血患者愈合影响探析[J].中国老年保健医学,2016,14(3):68.
[9] 张强.传统开颅手术与显微镜下微创手术治疗基底节区高血压脑出血的临床疗效比较[J].医学综述,2016,22(6):1246-1248.
[10] 杜新亮,武强.微创定向置软管吸引术与开颅脑内血肿清除术治疗中度脑出血疗效分析[J].航空航天医学杂志,2015,26(9):1102-1103.