中医内外合治方案治疗社区获得性肺炎远期疗效观察

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英文篇名：Long-Term Effect Observation of Combined Internal and External Traditional Herbal Medicine for Pneumonia in Children 作者：魏巍 ; 王雪峰 ; 吴振起 ; 赵雪 ; 郝欧美 ; 王子 ; 张秀英 英文作者：WEI Wei;WANG Xuefeng;WU Zhenqi;ZHAO Xue;HAO Oumei;WANG Zi;ZHANG Xiuying;Liaoning University of Traditional Chinese Medicine;The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine; 关键词：儿童社区获得性肺炎 ; 中医内外合治 ; 预后 ; 远期疗效 英文关键词：children pneumonia;;combined internal and external traditional herbal medicine;;prognosis;;long-term effect 中文刊名：LNZY 英文刊名：Liaoning Journal of Traditional Chinese Medicine 机构：辽宁中医药大学;辽宁中医药大学附属医院; 出版日期：2018-12-13 16:11 出版单位：辽宁中医杂志 年：2019 期：v.46;No.502 基金：国家自然科学基金(81273800,81373687);; “十二五”中医药行业专项项目(201307007) 语种：中文; 页：LNZY201903043 页数：5 CN：03 ISSN：21-1128/R 分类号：144-148

摘要

目的:验证中医内外合治方案治疗社区获得性肺炎在远期疗效上的优势,为临床提供确切、可靠的治疗方案。方法:选取2014年4月14日—2016年1月1日期间全国9个地区10家三甲医院完全符合方案的1391例住院肺炎患儿,采用分层区组随机的方法,对比中医内外合治方案、中医内治方案、外治方案的远期疗效优势。结果:中医内外合治、中医内治、中医外治治疗儿童社区获得性肺炎(CAP)远期疗效突出,中医外治法主要可以减少预后90 d自汗的发生,减少预后15 d患上呼吸道感染的机率;中医内治法主要可以减少预后发生低热、咳嗽、盗汗、自汗的症状。结论:中医内外合治可减少儿童社区获得性肺炎预后发生低热、咳嗽、盗汗、自汗,降低发生上呼吸道感染的发生率。
        Objective: To explore the long-term effect of combined internal and external traditional herbal medicine for pneumonia in children for providing a reliable treatment protocols. Methods: A multicenter,stratified,block randomized,parallel-controlled trial was designed. The sample size was 1391 children,which recruited from ten hospitals nationwide from April 14 th,2014 to January 1 st,2016. We contrasted the long-term effect of combined internal and external traditional herbal medicine with internal traditional herbal medicine and external traditional herbal medicine. Results: The combined internal and external traditional herbal medicine group had the best long-term effect of disease. The external traditional herbal medicine can reduce spontaneous perspiration and upper respiratory tract infection rate of 90 days after treatment. The internal traditional herbal medicine can reduce low-grade fever,cough,night sweat,spontaneous perspiration and upper respiratory tract infection rate. Conclusion: Combined internal and external traditional herbal medicine can reduce the occurrence rate of low-grade fever,cough,night sweat,spontaneous perspiration and avoid upper respiratory infection after treatment.

引文

[1]付晓燕,辛徳莉,秦选光.儿童肺炎支原体感染流行病学、临床特点、发病机制及治疗研究进展[J].山东医药,2015(4):96-99.
    [2]陆权.儿童社区获得性肺炎管理指南(试行)(上)[J].中华儿科杂志,2007(2):83-90.
    [3]陆权,陈慧中,沈叙庄.儿童社区获得性肺炎管理指南(试行)(下)[J].中华儿科杂志,2007(3):223-230.
    [4]胡亚美,江载芳.诸福棠实用儿科学[M]. 7版.北京:人民卫生出版社,2012.
    [5]中华人民共和国卫生部.小儿四病防治方案[S].北京,1986.
    [6]汪受传,虞坚尔,丁樱.中医儿科学[M].北京:中国中医药出版社,2012:84-90.
    [7] Harris M,Clark J,Coote N,et. al. British Thoracic Society guidelines for the managementof community acquired pneumonia in children:update 2011[J]. Thorax,2011,66(Suppl 2):ii1-23.
    [8]庞丽敏.儿童支原体肺炎的发病特点调查分析[D].长春:吉林大学,2012.
    [9]赵才祥.小儿呼吸道感染肺炎支原体检测与分析[J].中华医院感染学杂志,2012,22:5045-5046.
    [10]柯莉芹,王凤美,李银洁,等.儿童肺炎支原体肺炎流行病学特征[J].中国当代儿科杂志,2013(1):33-36.
    [11]郝欧美,王雪峰,魏巍,等.中医内外合治综合方案改善小儿病毒性肺炎中医证候的多中心随机对照研究[J].中华中医药杂志,2017,32(11):5216-5220.
    [12]郝欧美,王雪峰.小儿肺炎的中医外治法研究进展[J].辽宁中医杂志,2016,43(4):883-885.
    [13]郝欧美,王雪峰,刘玉凤.敷胸巴布剂与敷胸散治疗小儿肺炎的临床疗效比较研究[J].中华中医药学刊,2016,34(4):820-822.
    [14]张亮,龙旭浩.姚晶莹教授拔火罐疗法促进小儿肺炎啰音吸收的经验[J].中国中西医结合儿科学,2013,5(4):310-311.
    [15]魏巍,白晓红,王雪峰,等.基于临床科研一体化平台儿童肺炎中医内外合治对主症影响的前瞻性研究[J].中国中西医结合儿科学,2013,5(4):323-325.
    [16]王力宁,王雪峰,原晓风,等.中医药治疗小儿肺炎喘嗽风热闭肺证、痰热闭肺证临床验证方案的多中心随机对照研究[J].中国中西医结合儿科学,2010,2(5):386-391.
    [17]王雪峰,刘芳,董丹,等.内外合治法治疗小儿肺炎临床疗效评价[J].中国中西医结合杂志,2005(6):536-539.