六味地黄膏摩促进幼鼠生长发育初探
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摘要
目的:观察六味地黄膏摩对幼鼠生长发育的影响。方法:取SD幼鼠28只,随机分为实验组和对照组各14只,实验组予六味地黄膏摩,对照组予凡士林膏摩,两组相同时间点检测体重,记录14天时睁眼数。结果:出生后28日两组幼鼠体重比较,实验组体重高于对照组(P<0.05);两组幼鼠14天睁眼数比较,实验组优于对照组(P<0.05)。结论:六味地黄膏摩能够通过透皮吸收发挥六味地黄复方制剂补益脾肾的功效,促进幼鼠的生长发育。
Objective: To observe the influence of six-ingredient rehmannia ointment rubbing on the growth and development of infant rats. Methods:28 infant SD rats were randomly divided into experimental group(n=14) and control group(n=14), the experimental group received ointment rubbing with six-ingredient rehmannia ointment while control group with Vaseline, detected weight of the two groups at the same time points and recorded the number of eyes open at the 14 th day. Results: Compared the weight of 28 days after birth, experimental group was significantly higher than that of control group(P<0.05); at the 14 th day, the number of eyes open in experimental group was better than that of control group(P<0.05). Conclusion:Six-ingredient rehmannia ointment rubbing can exert the efficiency of invigorating spleen and kidney in six-ingredient rehmannia compound preparation through percutaneous absorption to promote the growth and development of infant rats.
Objective: To observe the influence of six-ingredient rehmannia ointment rubbing on the growth and development of infant rats. Methods:28 infant SD rats were randomly divided into experimental group(n=14) and control group(n=14), the experimental group received ointment rubbing with six-ingredient rehmannia ointment while control group with Vaseline, detected weight of the two groups at the same time points and recorded the number of eyes open at the 14 th day. Results: Compared the weight of 28 days after birth, experimental group was significantly higher than that of control group(P<0.05); at the 14 th day, the number of eyes open in experimental group was better than that of control group(P<0.05). Conclusion:Six-ingredient rehmannia ointment rubbing can exert the efficiency of invigorating spleen and kidney in six-ingredient rehmannia compound preparation through percutaneous absorption to promote the growth and development of infant rats.
引文
[1]Tarik J.Preterm birth[N].The Media Center of World Heath Organizasion,2013-11(363).
[2]Blencowe H,Cousens S,Oestergaard M,et al.National,regional,and worldwide estimates of preterm birth rates in the year 2010with time trends since 1990 for selected countries:a systematic analysis and implications[J].Lancet,2012,379(9832):2162-2172.
[3]邰先桃,张星贺,何琪,等.促进早产低体重儿童生长发育的中药膏摩剂及制备方法[P].中国发明专利:201510994773.0,2015-12-28.
[4]徐叔云.药理实验方法学[M].北京:人民卫生出版社,2002:203.
[5]罗建设.早产低体重儿的护理进展[J].护理研究,2006,20(1):6-8.
[6]王付,许二平,张大伟.方剂学[M].北京:中国中医药出版社,2010:125.
[2]Blencowe H,Cousens S,Oestergaard M,et al.National,regional,and worldwide estimates of preterm birth rates in the year 2010with time trends since 1990 for selected countries:a systematic analysis and implications[J].Lancet,2012,379(9832):2162-2172.
[3]邰先桃,张星贺,何琪,等.促进早产低体重儿童生长发育的中药膏摩剂及制备方法[P].中国发明专利:201510994773.0,2015-12-28.
[4]徐叔云.药理实验方法学[M].北京:人民卫生出版社,2002:203.
[5]罗建设.早产低体重儿的护理进展[J].护理研究,2006,20(1):6-8.
[6]王付,许二平,张大伟.方剂学[M].北京:中国中医药出版社,2010:125.