缩硫脲分子改性聚丙烯腈纤维的制备与性能影响
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摘要
将经过筛选后的缩硫脲分子与水解后的聚丙烯腈(PAN)纤维通过共价偶联进行修饰。对化合物和纤维样品进行结构与性能表征。结果表明:筛选出的缩硫脲分子不仅表现出低毒性,且对酪氨酸酶抑制显著,水解后的PAN纤维表面成功接枝缩硫脲分子,且改性后的PAN纤维仍具有良好的热稳定性和力学性能。该改性方法简单、实用性强,可作为果蔬的存储包装材料,具有抑制果蔬褐变等应用价值。
Hydrolyzed PAN fiber were grafted by the thiosemicarbazone compound after bioactive screening by covalent coupling.The structures and properties of the fiber and biological compound were characterized.The results demonstrated that the selected thiosemicarbazone not only showed low toxicity,but also significantly inhibited tyrosinase.The surface of the hydrolyzed PAN fiber was successfully grafted with a thiosemicarbazone compound and the PAN fiber maintained good thermal stability and mechanical properties after surface graft-modification.The feasible and practical modification method had many potential applications in development of storage and packaging materials for inhibiting browning of fruits and vegetables.
Hydrolyzed PAN fiber were grafted by the thiosemicarbazone compound after bioactive screening by covalent coupling.The structures and properties of the fiber and biological compound were characterized.The results demonstrated that the selected thiosemicarbazone not only showed low toxicity,but also significantly inhibited tyrosinase.The surface of the hydrolyzed PAN fiber was successfully grafted with a thiosemicarbazone compound and the PAN fiber maintained good thermal stability and mechanical properties after surface graft-modification.The feasible and practical modification method had many potential applications in development of storage and packaging materials for inhibiting browning of fruits and vegetables.
引文
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[3] Snchezferrer A,Rodríguezlópez J N,Garcíacanovas F,et al.Tyrosinase:a comprehensive review of its mechanism[J].Biochimica Et Biophysica Acta,1995,1247(1):1-11.
[4] 宋康康.抑制剂对酪氨酸酶的效应及其对黑色素生成调控的研究[D].厦门:厦门大学,2007.
[5] 任元林,王灵杰,刘甜甜.无卤阻燃聚丙烯腈纤维的制备及性能[J].高分子材料科学与工程,2016,32(5):130-133.
[6] 胡雪敏,肖长发,封严.胶原蛋白改性聚丙烯腈纤维制备及性能表征[J].功能材料,2013,44(10):1414-1417.
[7] Anderson F E,Duca C J,Scudi J V.Some heterocyclic thiosemicarbazones[J].Journal of the American Chemical Society,1951,73(10):4967-4968.
[8] 董雄伟.氨基硫脲类螯合剂由抑制SOD1调控活性氧ERK信号通路[D].武汉:华中师范大学,2015.
[9] Kubo I,Kinsthori I.2-Hydroxy-4-methoxybenzaldehyde:apotent tyrosinase inhibitor from African medicinal plants[J].Planta Medica,1999,65(1):19-22.
[10] Nihei K,Yamagiwa Y,Kamikawa T,et al.2-hydroxy-4-isopropylbenzaldehyde,apotent partial tyrosinase inhibitor[J].Bioorganic &Medicinal Chemistry Letters,2004,14(3):681-683.
[11] 陈清西,林建峰,宋康康.酪氨酸酶抑制剂的研究进展[J].厦门大学学报(自然版),2007,46(2):274-282.
[12] Goetghebeur M,Kermasha S.Inhibition of polyphenol oxidase by copper-metallothionein from Aspergillus niger[J].Phytochemistry,1996,42(4):935.
[13] 贾曌,杨彦功.腈纶表面接枝大豆蛋白质改性纤维的结构与性能[J].高分子材料科学与工程,2008,24(10):151-154.
[14] 贾曌.聚丙烯腈纤维的蛋白质表面接枝改性研究[D].哈尔滨:哈尔滨工业大学,2008.
[15] 刘艳春,何珠仪,白刚,等.腈纶织物的氰基水解酶/硼酸锌阻燃整理[J].纺织学报,2016,37(3):110-113.
[16] Zhang Z H,MA H F,Sun R J,et al.Structure and performance of collagen/PAN composite fiber[J].Polymer Materials Science &Engineering,2009,25(12):69-72.