玻璃酸钠联合曲安奈德治疗膝关节骨性关节炎的疗效研究
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摘要
目的探讨玻璃酸钠与曲安奈德联合治疗膝关节骨性关节炎的临床疗效。方法选取2017年5月～2018年7月期间我院收治的膝关节骨性关节炎患者82例,随机数字表法将患者分为观察组与对照组,每组41例。对照组患者接受玻璃酸钠治疗,观察组患者在此基础上联合曲安奈德治疗。比较两组治疗效果。结果治疗后,观察组VAS评分、Lysholm评分均优于对照组,差异有统计学意义(P<0.05)。观察组总有效率为95.12%,高于对照组的78.05%,差异有统计学意义(P<0.05)。结论玻璃酸钠联合曲安奈德治疗膝关节骨性关节炎的疗效显著,可有效缓解患者疼痛程度,改善膝关节功能,促进患者尽快康复。
Objective To investigate the clinical efficacy of sodium hyaluronate combined with triamcinolone acetonide in the treatment of knee osteoarthritis. Methods Eighty-two patients with knee osteoarthritis admitted to our hospital from May 2017 to July 2018 were enrolled. The patients were divided into observation group and control group by random number table method,with41 cases in each group. The patients in the control group were treated with sodium hyaluronate,and the patients in the observation group were treated with triamcinolone acetonide. Compare the effects of the two groups. Results After treatment,the VAS score and Lysholm score of the observation group were superior to the control group,and the difference was statistically significant(P<0.05). The total effective rate of the observation group was 95.12%,which was higher than that of the control group(78.05%),and the difference was statistically significant(P<0.05). Conclusion Sodium hyaluronate combined with triamcinolone acetonide is effective in the treatment of knee osteoarthritis,which can effectively alleviate the pain level,improve knee function and promote the recovery of patients as soon as possible.
Objective To investigate the clinical efficacy of sodium hyaluronate combined with triamcinolone acetonide in the treatment of knee osteoarthritis. Methods Eighty-two patients with knee osteoarthritis admitted to our hospital from May 2017 to July 2018 were enrolled. The patients were divided into observation group and control group by random number table method,with41 cases in each group. The patients in the control group were treated with sodium hyaluronate,and the patients in the observation group were treated with triamcinolone acetonide. Compare the effects of the two groups. Results After treatment,the VAS score and Lysholm score of the observation group were superior to the control group,and the difference was statistically significant(P<0.05). The total effective rate of the observation group was 95.12%,which was higher than that of the control group(78.05%),and the difference was statistically significant(P<0.05). Conclusion Sodium hyaluronate combined with triamcinolone acetonide is effective in the treatment of knee osteoarthritis,which can effectively alleviate the pain level,improve knee function and promote the recovery of patients as soon as possible.
引文
[1]叶霖,王友莲.类风湿关节炎的中西医发病机制综述[J].江西医药,2017,52(1):88-91.
[2]曾秋涛,宋洋,林勇,等.关节腔清理术治疗膝关节痛风性关节炎的临床研究[J].江西医药,2017,52(11):1150-1151.
[3]程金辉,陈钢.腰椎小关节骨性关节炎源性慢性腰痛研究进展[J].江西医药,2017,52(5):466-468.
[4]朱勇,李艺彬,王世捷,等.关节镜清理术配合口服独活寄生汤治疗膝骨关节炎肝肾亏虚证[J].中医正骨,2018,30(9):79-80+83.
[5]于新.曲安奈德联合玻璃酸钠注射治疗中老年退行性膝关节炎的临床疗效[J].中国药物经济学,2018,13(11):96-99.
[6]周子皓,田丰德,安宁,等.臭氧联合玻璃酸钠治疗膝关节骨性关节炎的临床疗效[J].临床医药文献电子杂志,2017,4(67):13229-13229.
[7]朱鑫鑫,沈金明.玻璃酸钠联合复方倍他米松注射液治疗膝关节骨性关节炎的临床疗效观察[J].中国现代医生,2018,27(6):90-93.
[8]王建刚.玻璃酸钠与曲安奈德腔内注射对骨性关节炎患者功能康复的影响观察[J].中外医学研究,2018,16(30):168-169.
[9]潘琪豹.玻璃酸钠、曲安奈德联合用药对退行性膝关节炎的治疗效果[J].中外医学研究,2017,15(16):24-25.
[10]徐雪芬,汪萌,林成尧.老年膝关节骨性关节炎患者手术治疗后行玻璃酸钠联合曲安奈德腔内注射的临床疗效[J].浙江创伤外科,2017,22(5):862-863.
[11]于新.曲安奈德联合玻璃酸钠注射治疗中老年退行性膝关节炎的临床疗效[J].中国药物经济学,2018,13(11):96-99.
[12]王设,过承兵,缪贤林.玻璃酸钠与曲安奈德腔内注射对骨性关节炎患者功能康复的影响[J].当代医学,2018,24(11):61-63.
[13]韩秉和.椎间盘镜下髓核摘除术中联合硬膜外注射曲安奈德和玻璃酸钠对腰椎间盘突出症的疗效[J].河南医学研究,2017,26(8):1443-1444.
[14]陈永华,徐龙,王宝虎.玻璃酸钠注射液联合曲安奈德复合液硬膜外注射治疗腰椎间盘突出症疗效观察[J].浙江临床医学,2017,19(1):77-78.
[2]曾秋涛,宋洋,林勇,等.关节腔清理术治疗膝关节痛风性关节炎的临床研究[J].江西医药,2017,52(11):1150-1151.
[3]程金辉,陈钢.腰椎小关节骨性关节炎源性慢性腰痛研究进展[J].江西医药,2017,52(5):466-468.
[4]朱勇,李艺彬,王世捷,等.关节镜清理术配合口服独活寄生汤治疗膝骨关节炎肝肾亏虚证[J].中医正骨,2018,30(9):79-80+83.
[5]于新.曲安奈德联合玻璃酸钠注射治疗中老年退行性膝关节炎的临床疗效[J].中国药物经济学,2018,13(11):96-99.
[6]周子皓,田丰德,安宁,等.臭氧联合玻璃酸钠治疗膝关节骨性关节炎的临床疗效[J].临床医药文献电子杂志,2017,4(67):13229-13229.
[7]朱鑫鑫,沈金明.玻璃酸钠联合复方倍他米松注射液治疗膝关节骨性关节炎的临床疗效观察[J].中国现代医生,2018,27(6):90-93.
[8]王建刚.玻璃酸钠与曲安奈德腔内注射对骨性关节炎患者功能康复的影响观察[J].中外医学研究,2018,16(30):168-169.
[9]潘琪豹.玻璃酸钠、曲安奈德联合用药对退行性膝关节炎的治疗效果[J].中外医学研究,2017,15(16):24-25.
[10]徐雪芬,汪萌,林成尧.老年膝关节骨性关节炎患者手术治疗后行玻璃酸钠联合曲安奈德腔内注射的临床疗效[J].浙江创伤外科,2017,22(5):862-863.
[11]于新.曲安奈德联合玻璃酸钠注射治疗中老年退行性膝关节炎的临床疗效[J].中国药物经济学,2018,13(11):96-99.
[12]王设,过承兵,缪贤林.玻璃酸钠与曲安奈德腔内注射对骨性关节炎患者功能康复的影响[J].当代医学,2018,24(11):61-63.
[13]韩秉和.椎间盘镜下髓核摘除术中联合硬膜外注射曲安奈德和玻璃酸钠对腰椎间盘突出症的疗效[J].河南医学研究,2017,26(8):1443-1444.
[14]陈永华,徐龙,王宝虎.玻璃酸钠注射液联合曲安奈德复合液硬膜外注射治疗腰椎间盘突出症疗效观察[J].浙江临床医学,2017,19(1):77-78.