呼出气一氧化氮在支气管哮喘诊断及治疗效果评估中的价值研究
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摘要
目的:探讨呼出气一氧化氮在支气管哮喘诊断中的应用效果及对治疗效果的评估价值。方法:选取46例支气管炎哮喘患者(观察组),同期选取46例非支气管哮喘患者(对照组),对呼出气一氧化氮的诊断情况进行分析。结果:PEF、FEV_1、FVC、FeNO指标方面,对照组和观察组对比,差异有统计学意义(P<0.05)。且治疗后,观察组的各项指标均优于治疗前,差异有统计学意义(P<0.05)。结论:临床对支气管哮喘患者应用呼出气一氧化氮诊断,方案可靠,且能够有效评估后期治疗情况,故值得推广。
Objective To investigate the effect of exhaled nitric oxide in the diagnosis of bronchial asthma and evaluate the therapeutic effect.Method 46 patients with bronchitis and asthma(observation group) and 46 patients with non-bronchial asthma(control group) were selected to analyze the diagnosis of exhaled nitric oxide.Results There were significant differences in PEF,FEV_1,FVC and FeNO between the control group and the observation group(P<0.05).After treatment,all indexes in the observation group were better than those before treatment(P<0.05).Conclusion The clinical application of exhaled nitric oxide in the diagnosis of bronchial asthma is reliable,and can effectively evaluate the late treatment,so it is worth promoting.
Objective To investigate the effect of exhaled nitric oxide in the diagnosis of bronchial asthma and evaluate the therapeutic effect.Method 46 patients with bronchitis and asthma(observation group) and 46 patients with non-bronchial asthma(control group) were selected to analyze the diagnosis of exhaled nitric oxide.Results There were significant differences in PEF,FEV_1,FVC and FeNO between the control group and the observation group(P<0.05).After treatment,all indexes in the observation group were better than those before treatment(P<0.05).Conclusion The clinical application of exhaled nitric oxide in the diagnosis of bronchial asthma is reliable,and can effectively evaluate the late treatment,so it is worth promoting.
引文
[1] 王霞,魏春华,王新强,等.呼出气一氧化氮对支气管哮喘的诊断价值及其与气道炎症的相关性分析[J].国际呼吸杂志,2017,37(12):905.
[2] 孙明祥,刘本洪,王明珍.测定一氧化氮呼出气应用在支气管哮喘诊断和治疗中的临床观察[J].检验医学与临床,2017,14(A01):98.
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[5] 刘国华,袁晓梅,张志强,等.呼出气一氧化氮在嗜酸性粒细胞表型支气管哮喘患者的诊断及吸入糖皮质激素治疗效果评价中的价值[J].新乡医学院学报,2017,34(9):836.
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[7] 高玮,郭海英,周新,等.呼出气一氧化氮检测对咳嗽变异性哮喘的诊断价值[J].国际呼吸杂志,2016,36(16):1201.
[8] Matsuzaki S,Darcha C.Adenosine triphosphate-binding cassette transporter G2 expression in endometriosis and in endometrium form patients with and without endometriosis[J].Fertil Steril,2012,98(6):1512.
[2] 孙明祥,刘本洪,王明珍.测定一氧化氮呼出气应用在支气管哮喘诊断和治疗中的临床观察[J].检验医学与临床,2017,14(A01):98.
[3] 张雪,费霞,鲍鲁红,等.支气管哮喘患者呼出气一氧化氮与小气道功能的相关性及其影响因素[J].上海医学,2017,10(2):84.
[4] 刘敏,许西琳,刘冬,等.呼出气一氧化氮和外周血嗜酸性粒细胞百分率对支气管哮喘诊断和病情评估价值[J].中华实用诊断与治疗杂志,2017,31(8):769.
[5] 刘国华,袁晓梅,张志强,等.呼出气一氧化氮在嗜酸性粒细胞表型支气管哮喘患者的诊断及吸入糖皮质激素治疗效果评价中的价值[J].新乡医学院学报,2017,34(9):836.
[6] Fassbender A,Verbeeck N,B?rnigen D,et al.Combined mRNA microarray and proteomic analysis of eutopic endometrium of women with and without endometriosis[J].Hum Reprod,2012,27(7):2020-9.
[7] 高玮,郭海英,周新,等.呼出气一氧化氮检测对咳嗽变异性哮喘的诊断价值[J].国际呼吸杂志,2016,36(16):1201.
[8] Matsuzaki S,Darcha C.Adenosine triphosphate-binding cassette transporter G2 expression in endometriosis and in endometrium form patients with and without endometriosis[J].Fertil Steril,2012,98(6):1512.