穴位贴敷在先兆流产中的临床应用概况
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摘要
动物实验证实了中药穴位贴敷外治法具有肯定的疗效,中药中的有效成分可以通过皮肤进入血液循环,产生与其他给药途径相同的药理作用。本综述选取的21篇文献中穴位贴敷治疗先兆流产用药以桑寄生、菟丝子、续断、杜仲等使用频次较高。在穴位配伍方面,以神阙穴、肾俞为主穴搭配其他穴位较为常见,关元、涌泉作为主穴出现的频次也较高。现代研究对于穴位贴敷在先兆流产中的疗效评估多选取继续妊娠率、中医证候评分以及孕酮、人绒毛膜促性腺激素、雌二醇等性激素的变化。但相关研究对穴位贴敷的作用机制未能予以明确,同时也不能将所选药物及穴位如何反应在疗效指标上予以明确。
Animal experiments have proved that the effective ingredients of TCM can enter into the blood circulation through the skin and produce the same pharmacological action as other administration routes. Among the 21 papers selected in this review, Herba Taxilli, Semen Cuscutae, Radix Dipsaci,Cortex Eucommiae were used more frequently in acupoints application of TCM. In the compatibility of acupoints, it is common to use Shenque( RN8) and Shenshu( BL23) as main acupoints, Guanyuan(RN4) and Yongquan(KI1) as main acupoints appeared also frequently. In modern studies, the efficacy evaluation of acupoint application in threatened abortion is mainly based on the continuous pregnancy rate,TCM syndrome score, and the changes of progesterone, human chorionic gonadotropin, estradiol.However, the mechanism of acupoint application has not been clarified in relevant studies, nor can the selected medicine and acupoints how react in the therapeutic indicators be clarified.
Animal experiments have proved that the effective ingredients of TCM can enter into the blood circulation through the skin and produce the same pharmacological action as other administration routes. Among the 21 papers selected in this review, Herba Taxilli, Semen Cuscutae, Radix Dipsaci,Cortex Eucommiae were used more frequently in acupoints application of TCM. In the compatibility of acupoints, it is common to use Shenque( RN8) and Shenshu( BL23) as main acupoints, Guanyuan(RN4) and Yongquan(KI1) as main acupoints appeared also frequently. In modern studies, the efficacy evaluation of acupoint application in threatened abortion is mainly based on the continuous pregnancy rate,TCM syndrome score, and the changes of progesterone, human chorionic gonadotropin, estradiol.However, the mechanism of acupoint application has not been clarified in relevant studies, nor can the selected medicine and acupoints how react in the therapeutic indicators be clarified.
引文
[1]田从豁,彭冬青.中国贴敷治疗学[M].北京:中国中医药出版社,2015:4.
[2]李学智,梁繁荣.人体腧穴组织形态特异性研究的进展与现状[J].中国组织工程研究,2008,12(33):6535-6538.
[3]谢洋,余学庆.试述穴位贴敷的作用机理及其临床运用[J].中国医药指南,2008,6(24):320-322.
[4]刘起华,文谨,王菲,等.中药穴位给药应用研究概述[J].中国中医药信息杂志,2010,17(2):104-106.
[5]贺艳萍,肖小芹,邓桂明,等.中药穴位贴敷作用机理研究概况[J].中国中医药信息杂志,2017,24(3):134-136.
[6]赵欣纪,高希言,任珊.穴位贴敷对慢性萎缩性胃炎大鼠胃黏膜屏障功能的影响[J].河南中医学院学报,2005,21(2):20-22.
[7]张劲,张磊.穴位贴敷联合透明质酸钠治疗实验性日本大耳白兔膝骨关节炎的效果及作用机制[J].湖北中医杂志,2015,37(8):21-23.
[8]李金燕.安胎防漏汤结合中药敷贴治疗肾气虚型先兆流产的临床研究[J].广西中医药大学学报,2016,19(4):22-24.
[9]邓兰英,李海霞,廖潇潇,等.保胎膏配合黄体酮、HCG治疗先兆流产的临床观察[J].中国医药指南,2011,34(9):193-194.
[10]刘啸风,崔笑德.补肾健脾方配合中药穴位敷贴治疗先兆流产临床研究[J].中医药临床杂志,2016,28(4):550-552.
[11]黄慧红,杨秀平,言彩蝶,等.神阙穴中药贴敷辅助治疗早期先兆流产疗效观察[J].广西中医药,2014,37(1):27-28.
[12]杨秀平,黄慧红,周爱珍,等.穴位贴敷辅助治疗早期先兆流产的护理[J].光明中医,2015,30(7):1527-1528.
[13]陆亚静.穴位贴敷治疗先兆流产104例[J].山东中医药杂志,2011,30(3):176.
[14]黄少雅,莫如冰.中药穴位敷贴治疗肾虚型先兆流产102例[J].中医外治杂志,2013,22(3):20-21.
[15]苏美英.中药穴位贴敷辅助治疗早期先兆流产的护理效果观察[J].云南中医中药杂志,2017,38(2):105-106.
[16]李静颖,叶利群,陈颖颖.中药穴位贴敷联合羽调音乐治疗肾虚型早期先兆流产40例[J].浙江中医杂志,2017,52(4):263.
[17]董萍培,孙津津,徐秀玲,等.安胎Ⅰ号穴位贴敷对肾虚型先兆流产患者中医证候的影响[J].全科医学临床与教育,201614(1):81-83.
[18]张春平,邢佳,章勤.中药穴位贴敷联合孕期干预治疗肾虚型胎动不安有效性研究[J].新中医,2016,48(10):207-209.
[19]董萍培.安胎Ⅰ号穴位贴敷改善肾虚型先兆流产患者症状的临床研究[D].杭州:浙江中医药大学,2016.
[20]郭珍,张红,李文优,等.神阙穴贴敷联合黄体酮注射液对肾虚型早期先兆流产的护理干预[J].中国中医药现代远程教育,2016,14(11):124-125.
[21]叶丹丹.中西医结合治疗肾虚血热型胎动不安疗效观察[J].浙江中西医结合杂志,2016,26(7):654-656.
[22]莫东平.中西医结合治疗先兆流产40例[J].实用中医药杂志,2013,29(5):376-377.
[23]沈桂琴,陈俊敏.中药神阙穴贴敷联合黄体酮对肾虚型早期先兆流产患者的护理干预[J].实用临床医药杂志,2014,18(22):85-88.
[24]曹宠华,聂清英.中药穴位贴敷联合西药治疗早期先兆流产30例[J].浙江中医杂志,2014,49(3):207-208.
[25]江欣柳,贺海霞.“桑砂女蜜”穴位贴敷在先兆流产患者运用的效果观察[J].今日药学,2013,23(2):112-113.
[26]苏艳霞,陆识映,等.补肾固胎汤结合安胎散敷脐治疗肾虚型早期先兆流产60例[J].中医外治杂志,2016,25(6):23-24.
[27]彭敏,林莉.自制安胎膏穴位热敷贴治疗早期先兆流产疗效观察[J].广西中医药大学学报,2016,19(2):34-35.
[28]郑俊民.经皮给药新剂型[M].北京:人民卫生出版社,2007:431.
[29]郭志清.穴位敷贴联合中西药治疗肾虚型早期先兆流产的临床疗效观察[D].成都:成都中医药大学,2015.
[30]龙弥弥.穴位贴敷配合寿胎丸加减治疗胎漏、胎动不安63例[J].内蒙古中医药,2016,35(8):101.
[2]李学智,梁繁荣.人体腧穴组织形态特异性研究的进展与现状[J].中国组织工程研究,2008,12(33):6535-6538.
[3]谢洋,余学庆.试述穴位贴敷的作用机理及其临床运用[J].中国医药指南,2008,6(24):320-322.
[4]刘起华,文谨,王菲,等.中药穴位给药应用研究概述[J].中国中医药信息杂志,2010,17(2):104-106.
[5]贺艳萍,肖小芹,邓桂明,等.中药穴位贴敷作用机理研究概况[J].中国中医药信息杂志,2017,24(3):134-136.
[6]赵欣纪,高希言,任珊.穴位贴敷对慢性萎缩性胃炎大鼠胃黏膜屏障功能的影响[J].河南中医学院学报,2005,21(2):20-22.
[7]张劲,张磊.穴位贴敷联合透明质酸钠治疗实验性日本大耳白兔膝骨关节炎的效果及作用机制[J].湖北中医杂志,2015,37(8):21-23.
[8]李金燕.安胎防漏汤结合中药敷贴治疗肾气虚型先兆流产的临床研究[J].广西中医药大学学报,2016,19(4):22-24.
[9]邓兰英,李海霞,廖潇潇,等.保胎膏配合黄体酮、HCG治疗先兆流产的临床观察[J].中国医药指南,2011,34(9):193-194.
[10]刘啸风,崔笑德.补肾健脾方配合中药穴位敷贴治疗先兆流产临床研究[J].中医药临床杂志,2016,28(4):550-552.
[11]黄慧红,杨秀平,言彩蝶,等.神阙穴中药贴敷辅助治疗早期先兆流产疗效观察[J].广西中医药,2014,37(1):27-28.
[12]杨秀平,黄慧红,周爱珍,等.穴位贴敷辅助治疗早期先兆流产的护理[J].光明中医,2015,30(7):1527-1528.
[13]陆亚静.穴位贴敷治疗先兆流产104例[J].山东中医药杂志,2011,30(3):176.
[14]黄少雅,莫如冰.中药穴位敷贴治疗肾虚型先兆流产102例[J].中医外治杂志,2013,22(3):20-21.
[15]苏美英.中药穴位贴敷辅助治疗早期先兆流产的护理效果观察[J].云南中医中药杂志,2017,38(2):105-106.
[16]李静颖,叶利群,陈颖颖.中药穴位贴敷联合羽调音乐治疗肾虚型早期先兆流产40例[J].浙江中医杂志,2017,52(4):263.
[17]董萍培,孙津津,徐秀玲,等.安胎Ⅰ号穴位贴敷对肾虚型先兆流产患者中医证候的影响[J].全科医学临床与教育,201614(1):81-83.
[18]张春平,邢佳,章勤.中药穴位贴敷联合孕期干预治疗肾虚型胎动不安有效性研究[J].新中医,2016,48(10):207-209.
[19]董萍培.安胎Ⅰ号穴位贴敷改善肾虚型先兆流产患者症状的临床研究[D].杭州:浙江中医药大学,2016.
[20]郭珍,张红,李文优,等.神阙穴贴敷联合黄体酮注射液对肾虚型早期先兆流产的护理干预[J].中国中医药现代远程教育,2016,14(11):124-125.
[21]叶丹丹.中西医结合治疗肾虚血热型胎动不安疗效观察[J].浙江中西医结合杂志,2016,26(7):654-656.
[22]莫东平.中西医结合治疗先兆流产40例[J].实用中医药杂志,2013,29(5):376-377.
[23]沈桂琴,陈俊敏.中药神阙穴贴敷联合黄体酮对肾虚型早期先兆流产患者的护理干预[J].实用临床医药杂志,2014,18(22):85-88.
[24]曹宠华,聂清英.中药穴位贴敷联合西药治疗早期先兆流产30例[J].浙江中医杂志,2014,49(3):207-208.
[25]江欣柳,贺海霞.“桑砂女蜜”穴位贴敷在先兆流产患者运用的效果观察[J].今日药学,2013,23(2):112-113.
[26]苏艳霞,陆识映,等.补肾固胎汤结合安胎散敷脐治疗肾虚型早期先兆流产60例[J].中医外治杂志,2016,25(6):23-24.
[27]彭敏,林莉.自制安胎膏穴位热敷贴治疗早期先兆流产疗效观察[J].广西中医药大学学报,2016,19(2):34-35.
[28]郑俊民.经皮给药新剂型[M].北京:人民卫生出版社,2007:431.
[29]郭志清.穴位敷贴联合中西药治疗肾虚型早期先兆流产的临床疗效观察[D].成都:成都中医药大学,2015.
[30]龙弥弥.穴位贴敷配合寿胎丸加减治疗胎漏、胎动不安63例[J].内蒙古中医药,2016,35(8):101.
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