低渗口服补液盐加锌制剂治疗小儿腹泻的临床效果观察

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英文篇名：Observation on clinical effect of low permeability oral rehydration salt and zinc preparation in the treatment of infantile diarrhea 作者：辛书智 英文作者：XIN Shu-zhi;Liaoning Fuxin People's Hospital of Mongolian Autonomous County; 关键词：低渗口服补液盐 ; 锌制剂 ; 小儿腹泻 ; 临床效果 英文关键词：Low permeability oral rehydration salt;;Zinc preparation;;Infantile diarrhea;;Clinical effect 中文刊名：ZWYY 英文刊名：Chinese Journal of Modern Drug Application 机构：辽宁省阜新蒙古族自治县人民医院; 出版日期：2018-02-10 出版单位：中国现代药物应用 年：2018 期：v.12 语种：中文; 页：ZWYY201803045 页数：3 CN：03 ISSN：11-5581/R 分类号：80-82

摘要

目的探讨低渗口服补液盐加锌制剂治疗小儿腹泻的临床效果。方法 98例小儿腹泻患儿,根据数字表法分对照组和观察组,每组49例。对照组采用单一低渗口服补液盐治疗,观察组采用低渗口服补液盐加锌制剂治疗。比较两组小儿腹泻缓解率;全身症状消失时间、止泻时间、脱水纠正时间;干预前后患儿精神状态、食欲、活力、睡眠情况。结果对照组患儿缓解率为81.63%,观察组患儿缓解率为97.96%,观察组小儿腹泻缓解率高于对照组,差异具有统计学意义(P<0.05)。观察组全身症状消失时间、止泻时间、脱水纠正时间(3.23±1.41)、(5.23±2.61)、(4.38±1.21)d短于对照组的(4.78±2.72)、(7.67±3.57)、(6.21±1.59)d,差异具有统计学意义(P<0.05)。干预前两组精神状态、食欲、活力、睡眠评分比较差异无统计学意义(P>0.05);干预后观察组精神状态、食欲、活力、睡眠评分分别为(22.36±1.24)、(22.93±0.42)、(23.76±1.87)、(22.36±0.23)分,优于对照组的(17.95±1.26)、(18.15±0.64)、(17.91±1.73)、(17.24±0.54)分,差异具有统计学意义(P<0.05)。结论低渗口服补液盐加锌制剂治疗小儿腹泻的临床效果确切,可有效加速症状消退,缩短病程,且有效改善患儿精神状态和生理活力,值得推广。
        Objective To discuss the clinical effect of low permeability oral rehydration salt and zinc preparation in the treatment of infantile diarrhea. Methods A total of 98 diarrhea children were divided by digital table method into control group and observation group, with 49 cases in each group. The control group was treated with low permeability oral rehydration salt, and the observation group was treated with low permeability oral rehydration salt and zinc preparation. Comparison were made on remission rate of infantile diarrhea, disappearance time of systemic symptoms, diarrhea time, dehydration correction time, mental state appetite, vitality, sleep situation before and after intervention between the two groups. Results The control group had remission rate as 81.63%, which was 97.96% in the observation group. The observation group had higher remission rate of infantile diarrhea than the control group, and the difference was statistically significant(P<0.05). The observation group had disappearance time of systemic symptoms, diarrhea time and dehydration correction time as(3.23±1.41),(5.23±2.61) and(4.38±1.21) d, which were shorter than(4.78±2.72),(7.67±3.57) and(6.21±1.59) d in the control group, and the difference was statistically significant(P<0.05). Before intervention, both groups had no statistically significant difference in mental state appetite,vitality and sleep score(P>0.05).After intervention,the observation group had mental state appetite,vitality and sleep score respectively as(22.36±1.24),(22.93±0.42),(23.76±1.87)and(22.36±0.23)points,which were all better than(17.95±1.26),(18.15±0.64),(17.91±1.73)and(17.24±0.54)points in the control group,and the difference was statistically significant(P<0.05).Conclusion Low permeability oral rehydration salt shows affirmative clinical effect in treating infantile diarrhea,and can effectively accelerate the withdrawal of symptoms,shorten the course of disease,and effectively improve the mental state and physiological vitality of the children.It is worth popularizing.

引文

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