表现为血疱的硬化性萎缩性苔藓一例并文献复习
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摘要
<正>临床资料患者,男,77岁。颈背部血疱2个月。2个月前无明显诱因颈部出现红色斑片,后逐渐扩大,中央增厚结痂。否认类似家族史及遗传病史。否认药物过敏史。体格检查:系统查体未见明显异常,全身浅表淋巴结未触及肿大。皮肤科检查:颈背部约5 cm×7 cm大暗红色血疱,中央增厚结痂(图1),生殖器、肛周、口腔等其他部位未见类似皮损。实验室检查未见明显异常。组织病理示:表皮角化过度,表皮变薄,基底层细胞液化变性,局部可见水疱,真皮浅层胶原纤维均一化
引文
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[9] 郑婷,张迪展,周桂芝.伴有大疱损害的硬化萎缩性苔藓1例[J].临床皮肤科杂志,2014,43(9):562-563.
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[11] Lima RS,Maquiné GA,Schettini AP,et al.Bullous and hemorrhagic lichen sclerosus--Case report[J].An Bras Dermatol,2015,90(3 Suppl 1):118-120.
[12] 刘园园,魏国,张春敏.冷冻治愈硬化性萎缩性苔藓伴血疱1例[J].中国麻风皮肤病杂志,2015,31(2):122-124.
[13] Quatrano NA,Shvartsbeyn M,Meehan SA,et al.Extragenital bullous lichen sclerosus[J].Dermatol Online J,2015,21(12):6.
[14] Vukicevic J.Extensive bullous lichen sclerosus et atrophicus[J].An Bras Dermatol,2016,91(5 suppl 1):81-83.
[15] Arnold N,Manway M,Stephenson S,et al.Extragenital bullous lichen sclerosus on the anterior lower extremities:report of a case and literature review[J].Dermatol Online J,2017,23(6):14.
[16] Luzar B,Neil SM,Calonje E.Angiokeratoma-like changes in extragenital and genital lichen sclerosus[J].J Cutan Pathol,2009,36:540-542.
[2] Arnold N,Manway M,Stephenson S,et al.Extragenital bullous lichen sclerosus on the anterior lower extremities:report of a case and literature review[J].Dermatol Online J,2017,23(6):14.
[3] Bolognia JL,Jorizzo JL,Rapini RP.皮肤病学[M].朱学骏,王宝玺,孙建方,等译.2版.北京:北京大学医学出版社,2014:1812-1813.
[4] 马东来,方凯,姜国调.大疱性出血性硬化萎缩性苔藓一例[J].中华皮肤科杂志,2001,34(6):469.
[5] 朱铁山,马东来,王宝玺.伴发血疱的泛发性硬化性萎缩性苔藓1例[J].临床皮肤科杂志,2002,31(1):37-38.
[6] Hoffner MV,Rodríguez-Pichardo A,García-Bravo B,et al.Bullous lichen sclerosus and atrophicus of the penis[J].Eur J Dermatol,2009,19(6):651-652.
[7] Madan V,Cox NH.Extensive bullous lichen sclerosus with scarring alopecia[J].Clin Exp Dermatol,2009,34(3):360-362.
[8] Kimura A,Kambe N,Satoh T,et al.Follicular keratosis and bullous formation are typical signs of extragenital lichen sclerosus[J].J Dermatol,2010,38(8):834-836.
[9] 郑婷,张迪展,周桂芝.伴有大疱损害的硬化萎缩性苔藓1例[J].临床皮肤科杂志,2014,43(9):562-563.
[10] Vink L,Starink TM.Bullous acral lichen sclerosus with milia[J].Clin Exp Dermatol,2014,39(3):400-401.
[11] Lima RS,Maquiné GA,Schettini AP,et al.Bullous and hemorrhagic lichen sclerosus--Case report[J].An Bras Dermatol,2015,90(3 Suppl 1):118-120.
[12] 刘园园,魏国,张春敏.冷冻治愈硬化性萎缩性苔藓伴血疱1例[J].中国麻风皮肤病杂志,2015,31(2):122-124.
[13] Quatrano NA,Shvartsbeyn M,Meehan SA,et al.Extragenital bullous lichen sclerosus[J].Dermatol Online J,2015,21(12):6.
[14] Vukicevic J.Extensive bullous lichen sclerosus et atrophicus[J].An Bras Dermatol,2016,91(5 suppl 1):81-83.
[15] Arnold N,Manway M,Stephenson S,et al.Extragenital bullous lichen sclerosus on the anterior lower extremities:report of a case and literature review[J].Dermatol Online J,2017,23(6):14.
[16] Luzar B,Neil SM,Calonje E.Angiokeratoma-like changes in extragenital and genital lichen sclerosus[J].J Cutan Pathol,2009,36:540-542.