2011-2015年我国医院抗菌药物使用评价研究
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摘要
目的:了解国内抗菌药物使用情况,为合理用药相关制度的推进提供数据支撑。方法:通过比较2011-2015年全国抗菌药物临床应用监测网中心成员单位抗菌药物使用情况,分析全国抗菌药物临床应用专项整治活动以来住院患者抗菌药物使用控制情况,比较分析不同药物类别的使用量、使用强度以及不同省、市、自治区的使用强度及其变化趋势。结果:全国抗菌药物临床应用专项整治活动以来,用药频度最大的抗菌药物类别始终是三代头孢菌素、二代头孢菌素、喹诺酮类抗感染药等;三代头孢菌素和二代头孢菌素年消耗量呈缓慢下降趋势。结论:抗菌药物专项整治活动在抗菌药物使用控制上取得了一定成绩,但仍有提升的空间,应该进一步加大对抗菌药物使用的管理。
Objectives: To understand the use of antibiotics in China and provide data support for the promotion of rational drug use related systems. Methods: By comparing the use of antimicrobial agents in the clinical application of national antibacterial drugs in 2011-2015, analyzing the use of antibiotics in hospitalized patients since the national antibacterial drug clinical application special rectification activities, and comparatively analyzing the usage and intensity of different drug categories. As well as the intensity of use and trends of different provinces, autonomous regions and municipalities, the overall evaluation of the effectiveness of special rectification activities. Results: Since the study found that the most effective antibiotics have been the third-generation cephalosporins, second-generation cephalosporins, and quinolone anti-infectives since the special rectification activities. At the same time, the third-generation cephalosporins and second-generation cephalosporins have accumulated. Conclusion: The special rectification activities of antibacterial drugs have achieved certain results in the control of antibacterial use, but there is still room for efforts, and the management of antibacterial use should be further increased.
Objectives: To understand the use of antibiotics in China and provide data support for the promotion of rational drug use related systems. Methods: By comparing the use of antimicrobial agents in the clinical application of national antibacterial drugs in 2011-2015, analyzing the use of antibiotics in hospitalized patients since the national antibacterial drug clinical application special rectification activities, and comparatively analyzing the usage and intensity of different drug categories. As well as the intensity of use and trends of different provinces, autonomous regions and municipalities, the overall evaluation of the effectiveness of special rectification activities. Results: Since the study found that the most effective antibiotics have been the third-generation cephalosporins, second-generation cephalosporins, and quinolone anti-infectives since the special rectification activities. At the same time, the third-generation cephalosporins and second-generation cephalosporins have accumulated. Conclusion: The special rectification activities of antibacterial drugs have achieved certain results in the control of antibacterial use, but there is still room for efforts, and the management of antibacterial use should be further increased.
引文
[1]叶云.氟喹诺酮类抗菌药使用频度与常见细菌耐药率的相关研究[J].中国药物警戒,2015,12(7):424-427.
[2]夏诚兰.医院住院抗菌药物使用率及使用强度管理指标的制定[J].影像研究与医学应用,2017,1(6):28-29.
[3]邹晓旭,张敏,赵露,等.我国抗菌药物临床应用专项整治情况调查与分析[J].中国医院管理,2014,34(2):10-12.
[4]卓超,钟南山.抗菌药物与临床合理应用概述[J].中华关节外科杂志(电子版),2014,8(5):682-686.
[5]金兰姬.多重耐药菌医院感染预防控制措施[J].中国保健营养,2016,26(18):284-285.
[6]张丽.多重耐药菌医院感染的预防和控制措施解析[J].中国现代药物应用,2015,9(4):110-111.
[7]卫生部.2012年全国抗菌药物临床应用专项整治活动方案[EB/OL].(2012-03-06)[2018-01-29].http://www.carss.cn/Policy/Details/30.
[2]夏诚兰.医院住院抗菌药物使用率及使用强度管理指标的制定[J].影像研究与医学应用,2017,1(6):28-29.
[3]邹晓旭,张敏,赵露,等.我国抗菌药物临床应用专项整治情况调查与分析[J].中国医院管理,2014,34(2):10-12.
[4]卓超,钟南山.抗菌药物与临床合理应用概述[J].中华关节外科杂志(电子版),2014,8(5):682-686.
[5]金兰姬.多重耐药菌医院感染预防控制措施[J].中国保健营养,2016,26(18):284-285.
[6]张丽.多重耐药菌医院感染的预防和控制措施解析[J].中国现代药物应用,2015,9(4):110-111.
[7]卫生部.2012年全国抗菌药物临床应用专项整治活动方案[EB/OL].(2012-03-06)[2018-01-29].http://www.carss.cn/Policy/Details/30.