配方注册婴幼儿配方乳粉中蛋白质及三聚氰胺含量测定分析
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摘要
目的通过测定婴幼儿配方乳粉中蛋白质及三聚氰胺含量,对我国现阶段配方注册的婴幼儿配方乳粉安全状况进行监测。方法婴幼儿配方乳粉中蛋白质的含量依照GB 5009.5-2016《食品安全国家标准食品中蛋白质的测定》中"第一法凯氏定氮法"进行检测;三聚氰胺的含量依照GB/T22388-2008《原料乳与乳制品中三聚氰胺检测方法》中"第一法高效液相色谱法"进行检测。结果样品中蛋白质含量均符合食品安全国家标准规定,且满足测定值不小于标签标示值80%的规定;三聚氰胺的含量均为未检出或低于检出限,符合原卫生部公告的限量值规定。结论根据食品安全国家标准或推荐标准的检测方法和评价指标,所检测的样品中蛋白质项目满足配方注册要求。
Objective To monitor the safety of infant formula milk powder registered in China by measuring the content of protein and melamine in infant formula milk powder. Methods Protein content in infant formula milk powder was determined according to the first method-Kjeldahl method in GB 5009.5-2016 National food safety standards-Determination of protein. The content of melamine was detected according to the first method-high performance liquid chromatography(HPLC) in GB/T 22388-2008 Testing methods for melamine in raw milk and dairy products. Results The protein content in the samples all met the national food safety standards, and the measured value was not less than 80% of the labeled value. Melamine content was not detected or less than the detection limit, in line with the limit value in the announcement of former ministry of health. Conclusion According to the testing methods and evaluation indexes of national food safety or recommended standards, the protein content in tested samples meet the requirements of formula registration.
Objective To monitor the safety of infant formula milk powder registered in China by measuring the content of protein and melamine in infant formula milk powder. Methods Protein content in infant formula milk powder was determined according to the first method-Kjeldahl method in GB 5009.5-2016 National food safety standards-Determination of protein. The content of melamine was detected according to the first method-high performance liquid chromatography(HPLC) in GB/T 22388-2008 Testing methods for melamine in raw milk and dairy products. Results The protein content in the samples all met the national food safety standards, and the measured value was not less than 80% of the labeled value. Melamine content was not detected or less than the detection limit, in line with the limit value in the announcement of former ministry of health. Conclusion According to the testing methods and evaluation indexes of national food safety or recommended standards, the protein content in tested samples meet the requirements of formula registration.
引文
[1]全国人民代表大会常务委员会.中华人民共和国食品安全法[EB/OL].[2015-04-24].http://www.gov.cn/zhengce/2015-04/25/content_2853643.htm.Standing Committee of the National People's Congress.Food safety law of the People's Republic of China[EB/OL].[2015-04-24].http://www.gov.cn/zhengce/2015-04/25/content_2853643.htm.
[2]国务院.国务院关于印发“十三五”国家食品安全规划和“十三五”国家药品安全规划的通知[EB/OL].[2017-02-21].http://www.gov.cn/zhengce/content/2017-02/21/content_5169755.htm.State Council.Notice of the State Council on Issuing the13th five-year national food safety plan and the 13th five-year national drug safety plan[EB/OL].[2017-02-21].http://www.gov.cn/zhengce/content/2017-02/21/content_5169755.htm.
[3]国家食品药品监督管理总局.《婴幼儿配方乳粉产品配方注册管理办法》解读[EB/OL].[2016-06-13].http://samr.cfda.gov.cn/WS01/CL1786/155761.html.China Food and Drug Administration.Interpretation on administrative measures for product formula registration of infants and young children formula milk powder[EB/OL].[2016-06-13].http://samr.cfda.gov.cn/WS01/CL1786/155761.html.
[4]国家食品药品监督管理总局.婴幼儿配方乳粉产品配方注册管理办法[EB/OL].[2016-06-06].http://samr.cfda.gov.cn/WS01/CL1975/223418.html.China Food and Drug Administration.Administrative measures for product formula registration of infants and young children formula milk powder[EB/OL].[2016-06-06].http://samr.cfda.gov.cn/WS01/CL1975/223418.html.
[5]宋玱玱,朱双良,田憬若,等.扬州市售婴幼儿乳粉中蛋白质及三聚氰胺的分析与评价[J].食品安全质量检测学报,2011,2(6):290-293.Song LL,Zhu SL,Tian JR,et al.Detection and evaluation of total protein andmelamine contents in infant formula[J].J Food Saf Qual,2011,2(6):290-293.
[6]陈婧,王旭,孙建平,等.几种问题乳粉蛋白质的分析[C].第三届中国乳业科技大会,2007:245-247.Cheng J,Wang X,Sun JP,et al.Analysis of protein content in some nonqualified milk powder[C].The 3rd China dairy science and technology conference,2007:245-247.
[7]国家食品药品监督管理总局.国家食品药品监督管理总局关于发布婴幼儿配方乳粉生产许可审查细则(2013版)的公告(2013年第49号)[EB/OL].[2013-12-16].http://samr.cfda.gov.cn/WS01/CL0053/95414.html.China Food and Drug Administration.Notice of the China Food and Drug Administration on the issuance of detailed rules for the review of production license for infant formula milk powder(2013 version)(No.49of 2013)[EB/OL].[2013-12-16].http://samr.cfda.gov.cn/WS01/CL0053/95414.html.
[8]GB 5009.5-2016食品安全国家标准食品中蛋白质的测定[S].GB 5009.5-2016 National food safety standard-Determination of protein in foods[S].
[9]GB/T 22388-2008原料乳与乳制品中三聚氰胺检测方法[S].GB/T 22388-2008 Testing method for melamine in raw milk and dairy products[S].
[10]GB 10765-2010食品安全国家标准婴儿配方食品[S].GB 10765-2010 National food safety standard-Infant formula[S].
[11]GB 10767-2010食品安全国家标准较大婴儿和幼儿配方食品[S].GB 10767-2010 National food safety standard-Older infants and young children formula[S].
[12]GB 28050-2011食品安全国家标准预包装食品营养标签通则[S].GB 28050-2011 National food safety standard-General principles for nutrition labelling of prepackaged foods[S].
[13]中华人民共和国卫生部中华人民共和国工业和信息化部中华人民共和国农业部国家工商行政管理总局国家质量监督检验检疫总局.卫生部等5部门关于三聚氰胺在食品中的限量值的公告(2011年第10号)[EB/OL].[2011-04-06].http://www.nhfpc.gov.cn/sps/s7891/201104/9f1311e1e97649f3a26a6b7f7b3d7ae3.shtml.Ministry of Health of the People's Republic of China,Ministry of Industry and Information Technology of the People's Republic of China,Ministry of Agriculture of the People's Republic of China,State Administration for Industry and Commerce,State Administration of Quality Supervision,Inspection and Quarantine.Announcement on the limited value of melamine in food by the Ministry of Health and other 5 departments(No.10 of 2011)[EB/OL].[2011-04-06].http://www.nhfpc.gov.cn/sps/s7891/201104/9f1311e1e97649f3a26a6b7f7b3d7ae3.shtml.
[14]国家卫生健康委员会.关于征求婴儿配方食品等9项食品安全国家标准及1项标准修改单(征求意见稿)意见的函[EB/OL].[2018-08-31].http://www.nhfpc.gov.cn/sps/s3593/201809/4f48037eba474f419b30e7f3368d0f46.shtml.National Health Commission of the People's Republic of China.Letter of solicitation for comments on 9 national standards of food safety,including infant formula food,and 1 revised list of standards(draft for comments)[EB/OL].[2018-08-31].http://www.nhfpc.gov.cn/sps/s3593/201809/4f48037eba474f419b30e7f3368d0f46.shtml.
[15]国务院办公厅.国务院办公厅关于推进奶业振兴保障乳品质量安全的意见[EB/OL].[2018-06-11].http://www.gov.cn/zhengce/content/2018-06/11/content_5297839.htm.General Office of the State Council.Guiding Opinions of the General Office of the State Council on promoting the revitalization of dairy industry to ensure the quality and safety of dairy products[EB/OL].[2018-06-11].http://www.gov.cn/zhengce/content/2018-06/11/content_5297839.htm.
[2]国务院.国务院关于印发“十三五”国家食品安全规划和“十三五”国家药品安全规划的通知[EB/OL].[2017-02-21].http://www.gov.cn/zhengce/content/2017-02/21/content_5169755.htm.State Council.Notice of the State Council on Issuing the13th five-year national food safety plan and the 13th five-year national drug safety plan[EB/OL].[2017-02-21].http://www.gov.cn/zhengce/content/2017-02/21/content_5169755.htm.
[3]国家食品药品监督管理总局.《婴幼儿配方乳粉产品配方注册管理办法》解读[EB/OL].[2016-06-13].http://samr.cfda.gov.cn/WS01/CL1786/155761.html.China Food and Drug Administration.Interpretation on administrative measures for product formula registration of infants and young children formula milk powder[EB/OL].[2016-06-13].http://samr.cfda.gov.cn/WS01/CL1786/155761.html.
[4]国家食品药品监督管理总局.婴幼儿配方乳粉产品配方注册管理办法[EB/OL].[2016-06-06].http://samr.cfda.gov.cn/WS01/CL1975/223418.html.China Food and Drug Administration.Administrative measures for product formula registration of infants and young children formula milk powder[EB/OL].[2016-06-06].http://samr.cfda.gov.cn/WS01/CL1975/223418.html.
[5]宋玱玱,朱双良,田憬若,等.扬州市售婴幼儿乳粉中蛋白质及三聚氰胺的分析与评价[J].食品安全质量检测学报,2011,2(6):290-293.Song LL,Zhu SL,Tian JR,et al.Detection and evaluation of total protein andmelamine contents in infant formula[J].J Food Saf Qual,2011,2(6):290-293.
[6]陈婧,王旭,孙建平,等.几种问题乳粉蛋白质的分析[C].第三届中国乳业科技大会,2007:245-247.Cheng J,Wang X,Sun JP,et al.Analysis of protein content in some nonqualified milk powder[C].The 3rd China dairy science and technology conference,2007:245-247.
[7]国家食品药品监督管理总局.国家食品药品监督管理总局关于发布婴幼儿配方乳粉生产许可审查细则(2013版)的公告(2013年第49号)[EB/OL].[2013-12-16].http://samr.cfda.gov.cn/WS01/CL0053/95414.html.China Food and Drug Administration.Notice of the China Food and Drug Administration on the issuance of detailed rules for the review of production license for infant formula milk powder(2013 version)(No.49of 2013)[EB/OL].[2013-12-16].http://samr.cfda.gov.cn/WS01/CL0053/95414.html.
[8]GB 5009.5-2016食品安全国家标准食品中蛋白质的测定[S].GB 5009.5-2016 National food safety standard-Determination of protein in foods[S].
[9]GB/T 22388-2008原料乳与乳制品中三聚氰胺检测方法[S].GB/T 22388-2008 Testing method for melamine in raw milk and dairy products[S].
[10]GB 10765-2010食品安全国家标准婴儿配方食品[S].GB 10765-2010 National food safety standard-Infant formula[S].
[11]GB 10767-2010食品安全国家标准较大婴儿和幼儿配方食品[S].GB 10767-2010 National food safety standard-Older infants and young children formula[S].
[12]GB 28050-2011食品安全国家标准预包装食品营养标签通则[S].GB 28050-2011 National food safety standard-General principles for nutrition labelling of prepackaged foods[S].
[13]中华人民共和国卫生部中华人民共和国工业和信息化部中华人民共和国农业部国家工商行政管理总局国家质量监督检验检疫总局.卫生部等5部门关于三聚氰胺在食品中的限量值的公告(2011年第10号)[EB/OL].[2011-04-06].http://www.nhfpc.gov.cn/sps/s7891/201104/9f1311e1e97649f3a26a6b7f7b3d7ae3.shtml.Ministry of Health of the People's Republic of China,Ministry of Industry and Information Technology of the People's Republic of China,Ministry of Agriculture of the People's Republic of China,State Administration for Industry and Commerce,State Administration of Quality Supervision,Inspection and Quarantine.Announcement on the limited value of melamine in food by the Ministry of Health and other 5 departments(No.10 of 2011)[EB/OL].[2011-04-06].http://www.nhfpc.gov.cn/sps/s7891/201104/9f1311e1e97649f3a26a6b7f7b3d7ae3.shtml.
[14]国家卫生健康委员会.关于征求婴儿配方食品等9项食品安全国家标准及1项标准修改单(征求意见稿)意见的函[EB/OL].[2018-08-31].http://www.nhfpc.gov.cn/sps/s3593/201809/4f48037eba474f419b30e7f3368d0f46.shtml.National Health Commission of the People's Republic of China.Letter of solicitation for comments on 9 national standards of food safety,including infant formula food,and 1 revised list of standards(draft for comments)[EB/OL].[2018-08-31].http://www.nhfpc.gov.cn/sps/s3593/201809/4f48037eba474f419b30e7f3368d0f46.shtml.
[15]国务院办公厅.国务院办公厅关于推进奶业振兴保障乳品质量安全的意见[EB/OL].[2018-06-11].http://www.gov.cn/zhengce/content/2018-06/11/content_5297839.htm.General Office of the State Council.Guiding Opinions of the General Office of the State Council on promoting the revitalization of dairy industry to ensure the quality and safety of dairy products[EB/OL].[2018-06-11].http://www.gov.cn/zhengce/content/2018-06/11/content_5297839.htm.