延安地区女性宫颈癌患者临床特征及相关因素分析
|
摘要
目的探讨延安地区女性宫颈癌患者临床特征及影响预后的相关因素。方法选取2010年6月至2012年6月延安市人民医院收治的的延安地区170例宫颈癌患者作为研究对象,回顾性分析其临床资料,总结患者的临床特征并对影响预后的相关因素进行单因素和多因素分析。结果鳞癌和腺癌患者在临床分期、肿瘤分型和淋巴结转移方面差异具有统计学意义(P <0. 05)。单因素分析结果显示,手术与否、肿瘤大小、病理类型、临床分期、肿瘤分型和淋巴结转移是影响宫颈癌患者预后的相关因素。多因素分析结果显示病理类型和治疗方案是影响宫颈癌患者预后的独立危险因素。结论影响延安地区女性宫颈癌患者预后的相关因素较多,主要是病理类型和治疗方案,临床上应当注意及时发现、诊断和治疗,提高患者生存率。
Objective To investigate the clinical characteristics and prognostic factors of cervical cancer patients in Yan'an. Methods 170 cervical cancer patients in our hospital from January 2014 to December 2016 were selected as the research object. The clinical data of the patients were analyzed retrospectively,and the clinical features of the patients were summarized. Univariate and multivariate analyses were performed to analyze the prognostic factors. Results There were statistically significant differences in clinical stage,tumor type and lymph node metastasis between squamous cell carcinoma and adenocarcinoma( P < 0. 05). According to univariate analysis,tumor size,pathological type,clinical stage,tumor type and lymph node metastasis were the prognostic factors.Multivariate analysis showed that clinical stage and lymph node metastasis were independent risk factors affecting theprognosis of cervical cancer patients. Conclusions There are many factors affecting the prognosis of cervical cancer patients in Yan'an,mainly including lymph node metastasis,clinical stage and pathological type. Clinical attention should be paid to timely detection,diagnosis and treatment to improve the survival rate of patients.
Objective To investigate the clinical characteristics and prognostic factors of cervical cancer patients in Yan'an. Methods 170 cervical cancer patients in our hospital from January 2014 to December 2016 were selected as the research object. The clinical data of the patients were analyzed retrospectively,and the clinical features of the patients were summarized. Univariate and multivariate analyses were performed to analyze the prognostic factors. Results There were statistically significant differences in clinical stage,tumor type and lymph node metastasis between squamous cell carcinoma and adenocarcinoma( P < 0. 05). According to univariate analysis,tumor size,pathological type,clinical stage,tumor type and lymph node metastasis were the prognostic factors.Multivariate analysis showed that clinical stage and lymph node metastasis were independent risk factors affecting theprognosis of cervical cancer patients. Conclusions There are many factors affecting the prognosis of cervical cancer patients in Yan'an,mainly including lymph node metastasis,clinical stage and pathological type. Clinical attention should be paid to timely detection,diagnosis and treatment to improve the survival rate of patients.
引文
[1] Norris MA,Walton RE,Christopher JS,et al. Canadian task force on preventive health care[J]. Recommendations on Screening for Cervical Cancer. CMAJ,2013,185(1):35-45.
[2] Munoz N,Bravo LE. Epidemiology of cervical cancer in Colombia[J]. Salud Publica de Mexico,2014 56(5):431-439.
[3]胡尚英,郑荣寿,赵方辉,等. 1989至2008年中国女性子宫颈癌发病和死亡趋势分析[J].中国医学科学院学报,2014,36(2):119-125.
[4]陆晓楣,李晶,刘畅浩,等.年轻宫颈癌患者的病理特点和预后分析[J].中华妇产科临床杂志,2011,12(1):10-12.
[5]蔡金凤,苏虹.年轻宫颈癌49例临床特点及早期诊断[J].中国现代药物应用,2010,4(20):61-62.
[6]雷艾华.宫颈癌临床病理特征及发病的相关影响因素[J].齐齐哈尔医学院学报,2013,34(13):1901-1902.
[7]彭俊,黄勇. 90例年轻宫颈癌患者临床特征及术后复发和预后相关因素分析[J].实用妇产科杂志,2016,32(1):44-45.
[8]顾彩珑,王玉萍.宫颈癌病理特征与预后的关系探讨[J].实用检验医师杂志,2012,4(3):153-156.
[9]谢林利,王彬,闫田静,等. 35岁以下年轻宫颈癌患者的临床病理特征以及危险因素分析[J].中国妇幼保健,2016,31(20):4147-4148.
[10]彭俊,黄勇. 90例年轻宫颈癌患者临床特征及术后复发和预后相关因素分析[J].实用妇产科杂志,2016,32(1):42-45.
[11]张毅娟,吴昌洪,赵苏萍,等.贵州省黔南州布依族和水族宫颈癌患者临床特征及预后比较[J].中国妇幼保健,2011,(29):4494-4496.
[12]刘丹,程雪花.年轻女性宫颈癌患者临床特征与早期宫颈癌预后因素分析[J].热带医学杂志,2017,17(1):32-34.
[13]丁金萍,蒋素玲,于华娜.郑州地区长期定居少数民族宫颈癌患者临床特征及相关因素分析[J].实用癌症杂志,2017,32(9):1540-1543.
[14]杨凌云,王红静,贾西彪,等. 35岁以下年轻宫颈癌患者临床病理特征及预后分析[J].广东医学,2012,33(18):2802-2804.
[15] Bielska LM,Krynicki R,Rabczenko D. Survival of cervi calcancer patients in selected regions of Poland in 1990-1996,in relation to some prognostic factors[J]. Przegl Epidemio1,2004,58(3):523-523.
[16]廖震华,陈增春,陈桂林,等. 190例宫颈癌患者临床病理特征及预后分析[J].中国肿瘤,2010,19(4):283-286.
[17]李梅芳.宫颈癌患者临床病理特征及预后分析[J].大家健康,2015,9(20):15-16.
[18]罗静,彭桂华.年轻宫颈癌的临床特征及其预后因素分析[J].中国医药指南,2013,11(7):493-495.
[2] Munoz N,Bravo LE. Epidemiology of cervical cancer in Colombia[J]. Salud Publica de Mexico,2014 56(5):431-439.
[3]胡尚英,郑荣寿,赵方辉,等. 1989至2008年中国女性子宫颈癌发病和死亡趋势分析[J].中国医学科学院学报,2014,36(2):119-125.
[4]陆晓楣,李晶,刘畅浩,等.年轻宫颈癌患者的病理特点和预后分析[J].中华妇产科临床杂志,2011,12(1):10-12.
[5]蔡金凤,苏虹.年轻宫颈癌49例临床特点及早期诊断[J].中国现代药物应用,2010,4(20):61-62.
[6]雷艾华.宫颈癌临床病理特征及发病的相关影响因素[J].齐齐哈尔医学院学报,2013,34(13):1901-1902.
[7]彭俊,黄勇. 90例年轻宫颈癌患者临床特征及术后复发和预后相关因素分析[J].实用妇产科杂志,2016,32(1):44-45.
[8]顾彩珑,王玉萍.宫颈癌病理特征与预后的关系探讨[J].实用检验医师杂志,2012,4(3):153-156.
[9]谢林利,王彬,闫田静,等. 35岁以下年轻宫颈癌患者的临床病理特征以及危险因素分析[J].中国妇幼保健,2016,31(20):4147-4148.
[10]彭俊,黄勇. 90例年轻宫颈癌患者临床特征及术后复发和预后相关因素分析[J].实用妇产科杂志,2016,32(1):42-45.
[11]张毅娟,吴昌洪,赵苏萍,等.贵州省黔南州布依族和水族宫颈癌患者临床特征及预后比较[J].中国妇幼保健,2011,(29):4494-4496.
[12]刘丹,程雪花.年轻女性宫颈癌患者临床特征与早期宫颈癌预后因素分析[J].热带医学杂志,2017,17(1):32-34.
[13]丁金萍,蒋素玲,于华娜.郑州地区长期定居少数民族宫颈癌患者临床特征及相关因素分析[J].实用癌症杂志,2017,32(9):1540-1543.
[14]杨凌云,王红静,贾西彪,等. 35岁以下年轻宫颈癌患者临床病理特征及预后分析[J].广东医学,2012,33(18):2802-2804.
[15] Bielska LM,Krynicki R,Rabczenko D. Survival of cervi calcancer patients in selected regions of Poland in 1990-1996,in relation to some prognostic factors[J]. Przegl Epidemio1,2004,58(3):523-523.
[16]廖震华,陈增春,陈桂林,等. 190例宫颈癌患者临床病理特征及预后分析[J].中国肿瘤,2010,19(4):283-286.
[17]李梅芳.宫颈癌患者临床病理特征及预后分析[J].大家健康,2015,9(20):15-16.
[18]罗静,彭桂华.年轻宫颈癌的临床特征及其预后因素分析[J].中国医药指南,2013,11(7):493-495.