桑寄生茶的应用历史与现代研究进展
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摘要
桑寄生茶为我国传统保健茶饮,但缺乏系统的整理总结,限制了其广泛应用和进一步开发。本文对我国别样茶中桑寄生茶的植物来源、应用历史、化学成分、药理活性和安全性等方面进行整理综述。桑寄生茶在我国两广地区具有悠久的饮用历史,能补肝肾,强筋骨,降压抗癌。现代研究表明,桑寄生茶含有黄酮类、萜类衍生物、挥发性成分、凝集素等成分,具有降血压,降血脂,降血糖,抗氧化,抗肿瘤,抗炎镇痛,利尿,神经保护等多种药理活性。但化学成分和药理活性的现代研究不够深入,以及寄主植物多样,没有规范,可能会对桑寄生茶的质量稳定和安全应用造成影响。
Taxillus chinensis Herb Tea is a traditional healthy tea in China,but its extensive applications and further developments are limited due to lack of systematic review.This paper summarizes its plant origin,application history,chemical constituents,pharmacological activities and safety.Taxillus chinensis Herb Tea has a long history of drinking in southern China,it can nourish liver and kidney,strengthen tendons and bones,lower blood pressure and fight cancer.Modern researches show that Taxillus chinensis Herb Tea contains chemical constituents such as flavonoids,hemiterpenoid derivatives,volatile constituents,lectin,etc.Moreover,its main pharmacological activities include hypotensive,hypolipidemic,hypoglycemic,blood glucose lowering,antioxidant and antitumor,anti-inflammatory and analgesic,diuretic,neuroprotective,etc.However,the modern researches on the chemical constituents and pharmacological activities of Taxillus chinensis Herb Tea are not thorough,and its host plants are diverse and irregular,which affect the quality stability and safe application of Taxillus chinensis Herb Tea.
Taxillus chinensis Herb Tea is a traditional healthy tea in China,but its extensive applications and further developments are limited due to lack of systematic review.This paper summarizes its plant origin,application history,chemical constituents,pharmacological activities and safety.Taxillus chinensis Herb Tea has a long history of drinking in southern China,it can nourish liver and kidney,strengthen tendons and bones,lower blood pressure and fight cancer.Modern researches show that Taxillus chinensis Herb Tea contains chemical constituents such as flavonoids,hemiterpenoid derivatives,volatile constituents,lectin,etc.Moreover,its main pharmacological activities include hypotensive,hypolipidemic,hypoglycemic,blood glucose lowering,antioxidant and antitumor,anti-inflammatory and analgesic,diuretic,neuroprotective,etc.However,the modern researches on the chemical constituents and pharmacological activities of Taxillus chinensis Herb Tea are not thorough,and its host plants are diverse and irregular,which affect the quality stability and safe application of Taxillus chinensis Herb Tea.
引文
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[3] 何春年,彭勇,肖伟,等.青钱柳神茶的应用历史与研究现状[J].中国现代中药,2012,14(5):62-68.
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[16] 李美蓉,李良群,马小亚,等.桑寄生化学成分的研究广寄生中d-儿茶素及槲皮素的分离和鉴定[J].华西药学杂志,1986,1(8):131-134.
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[18] 张协君,朱开昕,赵明惠,等.不同寄主来源的桑寄生药材槲皮苷与槲皮素含量分析[J].时珍国医国药,2011,22(7):1604-1606.
[19] 朱开昕,张协君,赵明惠,等.桑寄生嫩芽与老叶槲皮素含量对比研究[J].广西中医学院学报,2011,14(3):50-51.
[20] DING B,DAI Y,HOU Y L,et al.Four new hemiterpenoid derivatives from Taxillus chinensis[J].Fitoterapia,2013(86):1-5.
[21] 霍昕,高玉琼,杨迺嘉,等.桑寄生挥发性成分研究[J].生物技术,2008,18(2):47-49.
[22] 王誉霖,张文龙,龙小琴,等.不同寄主植物对桑寄生挥发性成分的影响研究[J].中国民族民间医药,2015(8):17-32.
[23] 李永华,苏本伟,张协君,等.寄主植物对桑寄生药材挥发性成分的影响研究[J].时珍国医国药,2012,23(3),574-578.
[24] 陈希宏,曾仲奎,刘荣华.桑寄生凝集素的纯化及部分性质研究[J].生物化学杂志,1992,8(2):150-156.
[25] 覃勇荣,农海花,藤英娟,等.桑寄生植物叶片维生素C含量的比较分析[J].时珍国医国药,2011,22(8):1890-1893.
[26] 夏建秋,万益群,付志红,等.ICP-AES 测定寿胎丸生药及煎煮液中的多种微量元素[J].光谱实验室,2013,30(1):272-279.
[27] 周汉华,刘晓龙,钱海兵,等.不同寄主上的桑寄生药材毒性的比较研究[J].中国实验方剂学杂志,2013,19(24):274-277.
[28] 李永华,卢栋,朱开昕,等.桑寄生及其夹竹桃科寄主植物强心苷含量相关性研究[J].时珍国医国药,2010,21(6):1397-1398.
[29] LU D,SU B W,LI Y H,et al.Study on salicin content correlation between taxilli herba and their willow host plants[J].J Med Plants Res,2012,6(12):2474-2477.
[30] 伍朝筼,章观德.马桑寄生及马桑子中内酯成分分析方法的研究[J].药学学报,1984,19(1):56-62.
[31] 唐家玲.桑寄生治疗高血压[J].中医杂志,2002,43(11):813.
[32] 叶立新,王继红,黄华利.桑寄生对肾性高血压大鼠血浆β-内啡肽浓度影响的量效作用[J].中国临床康复,2005,9(27):84-85.
[33] 张慧,黄蜚颖,刘人源.不同寄主桑寄生药材对原发性高血压大鼠降压作用的影响[J].中成药,2018,40(2):249-254.
[34] 华一俐,张融瑞,仇健明.中药桑寄生不同提取液的降脂作用研究[J].南京中医药大学学报,1995,11(2):86.
[35] 华一俐,吴慧平,张融瑞,等.桑寄生的降脂作用和抗脂质过氧化反应的研究[J].中国医药学报,1995,10(1):40-41.
[36] 汪宁,朱荃,周义维,等.桑寄生对培养的人HepG2 细胞葡萄糖消耗作用的影响[J].中医药学刊,2006,24(3):442-443.
[37] 苏娣,梁毅,周欣欣,等.桑寄生有效部位对白血病细胞株K562 抑制作用的研究[J].湖北中医药大学学报,2011,13(2):12-15.
[38] 张瑾,周欣欣,梁毅,等.桑寄生不同萃取部位的体外抗白血病作用研究[J].时珍国医国药,2011,22(10):2452-2454.
[39] ZHANG L,KOYYALAMUDI S R,JEONG Sang Chul,et al.Immunomodulatory activities of polysaccharides isolated from Taxillus chinensis and Uncaria rhyncophylla[J].Carbohyd Polym,2013,98(2):1458-1465.
[40] 巨鲜婷.桑寄生浸膏的抗炎和镇痛作用研究[J].杨凌职业技术学院学报,2012,11(2):5-7.
[41] 李蕴山,傅绍萱,韩锐,等.广寄生苷之利尿作用[J].药学学报,1959,7(1):1-4.
[42] 朱开昕,苏本伟,李永华.桑寄生药理作用及临床应用研究进展[J].现代医学与健康研究,2018,2(12):189-190.
[43] WANG Y,DENG M,ZHANG S Y,et al.Parasitic loranthus from Loranthaceae rather than Viscaceae potently inhibits fatty acid synthase and reduces body weight in mice[J].J Ethnopharm,2008(118):473-478.
[44] WANG Y,ZHANG S Y,MA X F,et al.Potent inhibition of fatty acid synthase by parasitic loranthus[Taxillus chinensis(DC.)Danser] and its constituent avicularin[J].J enzym inhib medi chem,2006:21(1):87-93.
[45] LIN Z,ANJANEYA S R,SUNDAR R K,et al.Antioxidant and Anti-inflammatory Activities of Selected Medicinal Plants Containing Phenolic and Flavonoid Compounds[J].J Agr Food Chem,2011(59):12361-12367.
[46] YOO J M,YANG J H,KIM Y S,et al.Inhibitory Effect of Loranthus parasiticus on IgE-Mediated Allergic Responses in RBL-2H3 Cells[J].Mediators Inflamm,2016(1):1-8.
[47] 彭树新,李啸红.桑寄生的遗传毒理学研究[J].中国优生与遗传杂志,2008,16(12):46-48.
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[2] 韩碧群,彭勇,肖培根,等.中国别样茶的整理研究[J].中国现代中药,2013,15(4):259-269.
[3] 何春年,彭勇,肖伟,等.青钱柳神茶的应用历史与研究现状[J].中国现代中药,2012,14(5):62-68.
[4] 国家药典委员会.中华人民共和国药典[M].北京:中国医药科技出版社,2015:299-300.
[5] 吴家荣,丘华兴.中药桑寄生原植物学名考[J].中草药,1981,12(5):32-35.
[6] 龚祝南,王铮涛,徐珞珊,等.中国桑寄生科Loranthaceae药用植物研究[J].中国野生植物资源,1996(1):11-15.
[7] 李开祥,梁晓静,覃平,等.桑寄生研究进展[J].广西林业科学,2011,40(4):311-314.
[8] 邓家刚,韦松基.广西道地药材[M].北京:中国中医药出版社,2007:350-355.
[9] 沈连生.神农本草经中药彩色图谱[M].北京:中国中医药出版社,1996:160.
[10] 刘排.寄生茶村野调查研究[J].乡村科技,2016,(2):67-68.
[11] 朱开昕,卢栋,赵明惠,等.不同季节桑寄生总黄酮含量测定[J].四川中医,2010,28(11):57-59.
[12] 谭支绍.药用寄生[M].南宁:广西科学技术出版社,1991:135.
[13] 高学敏.中药学[M].北京:中国中医药出版社,2014:197-198.
[14] 曾广方,陈仲良.国药中黄酮类的研究(Ⅵ)桑寄生化学成分的研究(第二报)广寄生中槲皮素及其配糖体的分离[J].药学学报,1957,5(4):317-325.
[15] 苏本伟,张协君,朱开昕,等.RP_HPLC法测定桑寄生中槲皮苷和槲皮素含量的提取方法比较[J].广西中医药.2012,35(4):53-55.
[16] 李美蓉,李良群,马小亚,等.桑寄生化学成分的研究广寄生中d-儿茶素及槲皮素的分离和鉴定[J].华西药学杂志,1986,1(8):131-134.
[17] 李永华,陈士林,卢栋,等.不同寄主植物桑寄生总黄酮含量研究[J].时珍国医国药,2009,20(12):3009-3010.
[18] 张协君,朱开昕,赵明惠,等.不同寄主来源的桑寄生药材槲皮苷与槲皮素含量分析[J].时珍国医国药,2011,22(7):1604-1606.
[19] 朱开昕,张协君,赵明惠,等.桑寄生嫩芽与老叶槲皮素含量对比研究[J].广西中医学院学报,2011,14(3):50-51.
[20] DING B,DAI Y,HOU Y L,et al.Four new hemiterpenoid derivatives from Taxillus chinensis[J].Fitoterapia,2013(86):1-5.
[21] 霍昕,高玉琼,杨迺嘉,等.桑寄生挥发性成分研究[J].生物技术,2008,18(2):47-49.
[22] 王誉霖,张文龙,龙小琴,等.不同寄主植物对桑寄生挥发性成分的影响研究[J].中国民族民间医药,2015(8):17-32.
[23] 李永华,苏本伟,张协君,等.寄主植物对桑寄生药材挥发性成分的影响研究[J].时珍国医国药,2012,23(3),574-578.
[24] 陈希宏,曾仲奎,刘荣华.桑寄生凝集素的纯化及部分性质研究[J].生物化学杂志,1992,8(2):150-156.
[25] 覃勇荣,农海花,藤英娟,等.桑寄生植物叶片维生素C含量的比较分析[J].时珍国医国药,2011,22(8):1890-1893.
[26] 夏建秋,万益群,付志红,等.ICP-AES 测定寿胎丸生药及煎煮液中的多种微量元素[J].光谱实验室,2013,30(1):272-279.
[27] 周汉华,刘晓龙,钱海兵,等.不同寄主上的桑寄生药材毒性的比较研究[J].中国实验方剂学杂志,2013,19(24):274-277.
[28] 李永华,卢栋,朱开昕,等.桑寄生及其夹竹桃科寄主植物强心苷含量相关性研究[J].时珍国医国药,2010,21(6):1397-1398.
[29] LU D,SU B W,LI Y H,et al.Study on salicin content correlation between taxilli herba and their willow host plants[J].J Med Plants Res,2012,6(12):2474-2477.
[30] 伍朝筼,章观德.马桑寄生及马桑子中内酯成分分析方法的研究[J].药学学报,1984,19(1):56-62.
[31] 唐家玲.桑寄生治疗高血压[J].中医杂志,2002,43(11):813.
[32] 叶立新,王继红,黄华利.桑寄生对肾性高血压大鼠血浆β-内啡肽浓度影响的量效作用[J].中国临床康复,2005,9(27):84-85.
[33] 张慧,黄蜚颖,刘人源.不同寄主桑寄生药材对原发性高血压大鼠降压作用的影响[J].中成药,2018,40(2):249-254.
[34] 华一俐,张融瑞,仇健明.中药桑寄生不同提取液的降脂作用研究[J].南京中医药大学学报,1995,11(2):86.
[35] 华一俐,吴慧平,张融瑞,等.桑寄生的降脂作用和抗脂质过氧化反应的研究[J].中国医药学报,1995,10(1):40-41.
[36] 汪宁,朱荃,周义维,等.桑寄生对培养的人HepG2 细胞葡萄糖消耗作用的影响[J].中医药学刊,2006,24(3):442-443.
[37] 苏娣,梁毅,周欣欣,等.桑寄生有效部位对白血病细胞株K562 抑制作用的研究[J].湖北中医药大学学报,2011,13(2):12-15.
[38] 张瑾,周欣欣,梁毅,等.桑寄生不同萃取部位的体外抗白血病作用研究[J].时珍国医国药,2011,22(10):2452-2454.
[39] ZHANG L,KOYYALAMUDI S R,JEONG Sang Chul,et al.Immunomodulatory activities of polysaccharides isolated from Taxillus chinensis and Uncaria rhyncophylla[J].Carbohyd Polym,2013,98(2):1458-1465.
[40] 巨鲜婷.桑寄生浸膏的抗炎和镇痛作用研究[J].杨凌职业技术学院学报,2012,11(2):5-7.
[41] 李蕴山,傅绍萱,韩锐,等.广寄生苷之利尿作用[J].药学学报,1959,7(1):1-4.
[42] 朱开昕,苏本伟,李永华.桑寄生药理作用及临床应用研究进展[J].现代医学与健康研究,2018,2(12):189-190.
[43] WANG Y,DENG M,ZHANG S Y,et al.Parasitic loranthus from Loranthaceae rather than Viscaceae potently inhibits fatty acid synthase and reduces body weight in mice[J].J Ethnopharm,2008(118):473-478.
[44] WANG Y,ZHANG S Y,MA X F,et al.Potent inhibition of fatty acid synthase by parasitic loranthus[Taxillus chinensis(DC.)Danser] and its constituent avicularin[J].J enzym inhib medi chem,2006:21(1):87-93.
[45] LIN Z,ANJANEYA S R,SUNDAR R K,et al.Antioxidant and Anti-inflammatory Activities of Selected Medicinal Plants Containing Phenolic and Flavonoid Compounds[J].J Agr Food Chem,2011(59):12361-12367.
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