基于三因制宜理论的非酒精性脂肪肝流行现状分析
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摘要
三因制宜理论是中医学中重要的防治原则之一,指出疾病的发生、发展以及转归因时、因地以及因人而异。非酒精性脂肪肝是我国最常见的流行病之一,与不同的性别、年龄、民族、职业及自然环境带来的独特饮食及生活方式等关系密切。故,文章基于中医三因制宜理论从天、地、人的角度对其流行现状做初步分析,旨在为非酒精性脂肪肝防治提供基础。
The theory of 'three factors suiting measures' is one of the important prevention and treatment principles in traditional Chinese medicine. It points out that the occurrence, development and attribution of diseases vary from place to place and from person to person. Nonalcoholic fatty liver disease(NAFLD) is one of the most common epidemics in China,which is closely related to the unique diet and lifestyle brought about by different gender, age, nationality, occupation and natural environment. Therefore, based on the'three factors' theory in traditional Chinese medicine, this paper makes a preliminary analysis of its epidemic status from the perspective of 'heaven', 'earth' and 'human', aiming at providing a basis for the prevention and treatment of non-alcoholic fatty liver disease.
The theory of 'three factors suiting measures' is one of the important prevention and treatment principles in traditional Chinese medicine. It points out that the occurrence, development and attribution of diseases vary from place to place and from person to person. Nonalcoholic fatty liver disease(NAFLD) is one of the most common epidemics in China,which is closely related to the unique diet and lifestyle brought about by different gender, age, nationality, occupation and natural environment. Therefore, based on the'three factors' theory in traditional Chinese medicine, this paper makes a preliminary analysis of its epidemic status from the perspective of 'heaven', 'earth' and 'human', aiming at providing a basis for the prevention and treatment of non-alcoholic fatty liver disease.
引文
[1]Li Z Z,Xue J,Chen P,et al.Prevalence of nonalcoholic fatty liver disease in mainland of China:A meta-analysis of published studies.Journal of Gastroenterology&Hepatology,2014,29(1):42-51
[2]Buzzetti E,Pinzani M,Tsochatzis E A.The multiple-hit pathogenesis of non-alcoholic fatty liver disease(NAFLD).Metabolism-clinical&Experimental,2016,65(8):1038-1048
[3]Dai H,Wang W,Chen R,et al.Lipid accumulation product is a powerful tool to predict non-alcoholic fatty liver disease in Chinese adults.Nutrition&Metabolism,2017,14(1):49
[4]李秀池,阮改清,吕加恩,等.某IT企业员工非酒精性单纯性脂肪肝和非酒精性脂肪性肝炎的初步调查及特征分析.临床肝胆病杂志,2017,33(7):1324-1327
[5]陈求真.广州市某高校社区人群非酒精性脂肪性肝病患病趋势变化及危险因素分析.广州:暨南大学,2015
[6]陈志宏,张娜,张玉喜,等.某市成人非酒精性脂肪肝患病率与民族、性别的影响分析.宁夏医学杂志,2017,39(3):249-251
[7]Perla F M,Prelati M,Lavorato M,et al.The role of lipid and lipoprotein metabolism in non-alcoholic fatty liver disease.Children,2017,4(6):46
[8]王垲涵.高血压患者的中医体质分析及相关心理问题的临床研究.北京:北京中医药大学,2017
[9]楼标雷,徐尔理,傅宁,等.海军飞行人员非酒精性脂肪肝调查及相关危险因素分析.海军医学杂志,2013,34(3):158-161
[10]楼标雷,徐尔理,傅宁,等.海军特勤人员非酒精性脂肪肝发病率及其危险因素流行病学调查.解放军预防医学杂志,2013,31(1):20-22
[11]斯琴,古艳婷.北京市朝阳区部分出租车司机非酒精性脂肪肝病危险因素的分析.中国医药导刊,2016,18(3):263-264
[12]康阳阳.中国成人慢性肾脏病患病率Meta分析.郑州:郑州大学,2017
[13]宋江美,咸亚静,莫合德斯·斯依提,等.乌鲁木齐市社区居民非酒精性脂肪肝流行现状调查.世界华人消化杂志,2016,24(12):1880-1884
[14]王小瑞,王晓荣,陈晓聿,等.包头市非酒精性脂肪肝及代谢综合征现状调查分析.疾病监测与控制,2016,10(10):819-821
[15]刘园,贺鹍鹏,强艳,等.某体检人群非酒精性脂肪肝的现状及其与高脂血症、肝功能异常的关系.宁夏医科大学学报,2015,37(3):267-271
[16]刘捷,王永红,罗蓉,等.ZJU指数筛查对健康体检人群非酒精性脂肪肝患病风险预测的价值评估:一项基于重庆市体检人群的单中心研究.重庆医科大学学报,2017,42(2):244-248
[17]郎学聪,滕华安,冯天雷.宜宾地区体检人群非酒精性脂肪肝患病率调查.现代预防医学,2015,42(4):719-720
[18]Xu C,Yi C,Lei X,et al.Serum complement C3 levels are associated with nonalcoholic fatty liver disease independently of metabolic features in Chinese population.Scientific Reports,2016,6:23279
[19]Qin L,Wang N,Bing H,et al.Neck circumference as an independent indicator to non-alcoholic fatty liver disease in non-obese men.Nutrition&Metabolism,2015,12(1):63
[20]郑洪.小者小异,大者大异——论地域中医流派的分化与拓展.中医杂志,2017,58(9):729-732
[21]Zhou Z,Zhou Q,Wang Y,et al.Prevalence of fatty liver disease and the economy in China:A systematic review.World J Gastroenterol,2015,21(18):5695-706
[22]张甜甜.Ⅰ山东内陆城市体检人群非酒精性脂肪肝相关危险因素分析Ⅱ促甲状腺素对胆固醇酯转运蛋白影响的研究.济南:山东大学,2016
[23]望长记,杨咏梅,陈雪媛.粤北山区非酒精性脂肪肝的患病率及相关影响因素分析.临床医学工程,2016,23(1):123-124
[24]Liu F Y,Hu L,Li Y X,et al.Effect of altitude chronic hypoxia on liver enzymes and its correlation with ACE/ACE2 in yak and migrated cattle.Chinese Journal of Applied Physiology,2015,31(3):272-275
[25]杨玥,周桂桐.申时治疗肝病理论探讨.安徽中医学院学报,2010,29(2):4-5
[26]Borck Patricia C,Batista Thiago M,Vettorazzi Jean F,et al.Nighttime light exposure enhances Reverbα-targeting microRNAs and contributes to hepatic steatosis.Metab Clin Exp,2018,85:250-258
[27]Chaix A,Lin T,Le H D,et al.Time-restricted feeding prevents obesity and metabolic syndrome in mice lacking a circadian clock.Cell Metab,2018,28(12):1-17
[28]刘天浩,张晨阳,韩思思,等.基于肠道微环境探讨“从肠治肺”的新内涵.中华中医药杂志,2018,31(12):5350-5352
[2]Buzzetti E,Pinzani M,Tsochatzis E A.The multiple-hit pathogenesis of non-alcoholic fatty liver disease(NAFLD).Metabolism-clinical&Experimental,2016,65(8):1038-1048
[3]Dai H,Wang W,Chen R,et al.Lipid accumulation product is a powerful tool to predict non-alcoholic fatty liver disease in Chinese adults.Nutrition&Metabolism,2017,14(1):49
[4]李秀池,阮改清,吕加恩,等.某IT企业员工非酒精性单纯性脂肪肝和非酒精性脂肪性肝炎的初步调查及特征分析.临床肝胆病杂志,2017,33(7):1324-1327
[5]陈求真.广州市某高校社区人群非酒精性脂肪性肝病患病趋势变化及危险因素分析.广州:暨南大学,2015
[6]陈志宏,张娜,张玉喜,等.某市成人非酒精性脂肪肝患病率与民族、性别的影响分析.宁夏医学杂志,2017,39(3):249-251
[7]Perla F M,Prelati M,Lavorato M,et al.The role of lipid and lipoprotein metabolism in non-alcoholic fatty liver disease.Children,2017,4(6):46
[8]王垲涵.高血压患者的中医体质分析及相关心理问题的临床研究.北京:北京中医药大学,2017
[9]楼标雷,徐尔理,傅宁,等.海军飞行人员非酒精性脂肪肝调查及相关危险因素分析.海军医学杂志,2013,34(3):158-161
[10]楼标雷,徐尔理,傅宁,等.海军特勤人员非酒精性脂肪肝发病率及其危险因素流行病学调查.解放军预防医学杂志,2013,31(1):20-22
[11]斯琴,古艳婷.北京市朝阳区部分出租车司机非酒精性脂肪肝病危险因素的分析.中国医药导刊,2016,18(3):263-264
[12]康阳阳.中国成人慢性肾脏病患病率Meta分析.郑州:郑州大学,2017
[13]宋江美,咸亚静,莫合德斯·斯依提,等.乌鲁木齐市社区居民非酒精性脂肪肝流行现状调查.世界华人消化杂志,2016,24(12):1880-1884
[14]王小瑞,王晓荣,陈晓聿,等.包头市非酒精性脂肪肝及代谢综合征现状调查分析.疾病监测与控制,2016,10(10):819-821
[15]刘园,贺鹍鹏,强艳,等.某体检人群非酒精性脂肪肝的现状及其与高脂血症、肝功能异常的关系.宁夏医科大学学报,2015,37(3):267-271
[16]刘捷,王永红,罗蓉,等.ZJU指数筛查对健康体检人群非酒精性脂肪肝患病风险预测的价值评估:一项基于重庆市体检人群的单中心研究.重庆医科大学学报,2017,42(2):244-248
[17]郎学聪,滕华安,冯天雷.宜宾地区体检人群非酒精性脂肪肝患病率调查.现代预防医学,2015,42(4):719-720
[18]Xu C,Yi C,Lei X,et al.Serum complement C3 levels are associated with nonalcoholic fatty liver disease independently of metabolic features in Chinese population.Scientific Reports,2016,6:23279
[19]Qin L,Wang N,Bing H,et al.Neck circumference as an independent indicator to non-alcoholic fatty liver disease in non-obese men.Nutrition&Metabolism,2015,12(1):63
[20]郑洪.小者小异,大者大异——论地域中医流派的分化与拓展.中医杂志,2017,58(9):729-732
[21]Zhou Z,Zhou Q,Wang Y,et al.Prevalence of fatty liver disease and the economy in China:A systematic review.World J Gastroenterol,2015,21(18):5695-706
[22]张甜甜.Ⅰ山东内陆城市体检人群非酒精性脂肪肝相关危险因素分析Ⅱ促甲状腺素对胆固醇酯转运蛋白影响的研究.济南:山东大学,2016
[23]望长记,杨咏梅,陈雪媛.粤北山区非酒精性脂肪肝的患病率及相关影响因素分析.临床医学工程,2016,23(1):123-124
[24]Liu F Y,Hu L,Li Y X,et al.Effect of altitude chronic hypoxia on liver enzymes and its correlation with ACE/ACE2 in yak and migrated cattle.Chinese Journal of Applied Physiology,2015,31(3):272-275
[25]杨玥,周桂桐.申时治疗肝病理论探讨.安徽中医学院学报,2010,29(2):4-5
[26]Borck Patricia C,Batista Thiago M,Vettorazzi Jean F,et al.Nighttime light exposure enhances Reverbα-targeting microRNAs and contributes to hepatic steatosis.Metab Clin Exp,2018,85:250-258
[27]Chaix A,Lin T,Le H D,et al.Time-restricted feeding prevents obesity and metabolic syndrome in mice lacking a circadian clock.Cell Metab,2018,28(12):1-17
[28]刘天浩,张晨阳,韩思思,等.基于肠道微环境探讨“从肠治肺”的新内涵.中华中医药杂志,2018,31(12):5350-5352
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