The dynamics of RUNX1-RUNX1T1 transcript levels after allogeneic hematopoietic stem cell transplantation predict relapse in patients with t(8;21) acute myeloid leukemia

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• 作者：Ya-Zhen Qin ; Yu Wang ; Lan-Ping Xu ; Xiao-Hui Zhang…
• 关键词：RUNX1 ; RUNX1T1 transcript levels ; Acute myeloid leukemia ; Allogeneic hematopoietic stem cell transplantation ; Relapse ; Donor lymphocyte infusion
• 刊名：Journal of Hematology & Oncology
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：10
• 期：1
• 全文大小：672KB
• 刊物主题：Oncology; Hematology; Cancer Research;
• 出版者：BioMed Central
• ISSN：1756-8722
• 卷排序：10

文摘

BackgroundThe optimal monitoring schedules and cutoff minimal residual disease (MRD) levels for the accurate prediction of relapse at all time points after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remain unclear in patients with t(8;21) acute myeloid leukemia (AML).