Ultrasound and dynamic functional imaging in vascular cognitive impairment and Alzheimer’s disease
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- 作者：Branko Malojcic ; Panteleimon Giannakopoulos ; Farzaneh A. Sorond…
- 关键词：Vascular cognitive impairment ; Vascular dementia ; Alzheimer disease ; Cerebral small vessel disease ; Ultrasonography ; Transcranial Doppler sonography ; Arterial spin labelling
- 刊名：BMC Medicine
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：15
- 期：1
- 全文大小：1213KB
- 刊物主题：Medicine/Public Health, general; Biomedicine, general;
- 出版者：BioMed Central
- ISSN：1741-7015
- 卷排序：15
文摘
BackgroundThe vascular contributions to neurodegeneration and neuroinflammation may be assessed by magnetic resonance imaging (MRI) and ultrasonography (US). This review summarises the methodology for these widely available, safe and relatively low cost tools and analyses recent work highlighting their potential utility as biomarkers for differentiating subtypes of cognitive impairment and dementia, tracking disease progression and evaluating response to treatment in various neurocognitive disorders.