Lower limb reconstruction in tumor patients using modular silver-coated megaprostheses with regard to perimegaprosthetic joint infection: a case series, including 100 patients and review of the literature
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- 作者：J. Schmolders ; S. Koob ; P. Schepers…
- 关键词：Megaprosthesis ; Periprosthetic joint infection ; Silver ; coated megaimplant ; Septic loosening ; Bone tumor ; Metastasis
- 刊名：Archives of Orthopaedic and Trauma Surgery
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：137
- 期：2
- 页码：149-153
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Orthopedics;
- 出版者：Springer Berlin Heidelberg
- ISSN：1434-3916
- 卷排序：137
文摘
Purpose and objectiveBone resection regarding adequate surgical margins is the treatment of choice for malignant bone tumors. In the case of metastasis-related complications, so-called skeletal-related events, it is highly important to achieve pain relief and a stable joint situation to re-mobilize the patients immediately following surgery. To bridge the often large osseous defect zones after tumor resection, both cemented and uncemented modular endoprosthetic systems are widely used. Patients undergoing tumor-related endoprosthetic orthopedic surgery are facing high risk for developing a periprosthetic joint infection (PJI). The immunocompromised condition due to anti-neoplastic treatment and long operation time with large exposure of tissue contributes to a high risk of infection.