Enhanced bioactivity of osteoblast-like cells on poly(lactic acid)/poly(methyl methacrylate)/nano-hydroxyapatite scaffolds for bone tissue engineering
详细信息 查看全文
- 作者：Zhicheng Rong (4)
Wen Zeng (1)
Yanshen Kuang (2)
Jianwei Zhang (1)
Xingyun Liu (3)
Yuan Lu (3)
Xiangrong Cheng (4)
4. Key Laboratory for Oral Biomedical Engineering ; Ministry of Education ; School and Hospital of Stomatology ; Wuhan University ; Wuhan ; 430079 ; China
1. School of Resource and Environmental Science ; Wuhan University ; Wuhan ; 430079 ; China
2. Zhongnan Hospital ; Wuhan University ; Wuhan ; 430079 ; China
3. School of Chemistry and Chemical Engineering ; Guangxi University ; Nanning ; 530004 ; China - 关键词：Hydroxyapatite nanoparticles ; Nanofibrous scaffolds ; Bioactivity ; Bone tissue engineering
- 刊名：Fibers and Polymers
- 出版年：2015
- 出版时间：February 2015
- 年：2015
- 卷：16
- 期：2
- 页码：245-253
- 全文大小：1,529 KB
- 参考文献：1. Jaiswal, A. K., Kadam, S. S., Soni, V. P., Bellare, J. R. (2013) Appl. Surf. Sci. 268: pp. 477 CrossRef
2. Tian, L., Prabhakaran, M. P., Ding, X., Ramakrishna, S. (2013) J. Biomater. Sci.-Polym. Ed. 24: pp. 1952 CrossRef
3. Fr枚hlich, M., Grayson, W. L., Wan, L. Q., Marolt, D., Drobnic, M., Vunjak-Novakovic, G. (2008) Curr. Stem Cell Res. Ther. 3: pp. 254 CrossRef
4. Prabhakaran, M. P., Venugopal, J., Ramakrishna, S. (2009) Acta Biomater. 5: pp. 2884 CrossRef
5. Li, W. J., Laurencin, C. T., Caterson, E. J., Tuan, R. S., Ko, F. K. (2002) J. Biomed. Mater. Res. Part B 60: pp. 613 CrossRef
6. Ishaug, S. L., Crane, G. M., Miller, M. J., Yasko, A. W., Yaszemski, M. J., Mikos, A. G. (1997) J. Biomed. Mater. Res. Part B 36: pp. 17 CrossRef
7. Webster, T. J., Siegel, R. W., Bizios, R. (1999) Biomaterials 20: pp. 1221 CrossRef
8. Frenot, A., Chronakis, I. S. (2003) Curr. Opin. Colloid Interface Sci. 8: pp. 64 CrossRef
9. Du, J., Li, X., Yang, C., Li, W., Huang, W., Huang, R., Zhou, X., Deng, H. (2013) Curr. Nanosci. 9: pp. 8
10. Ma, Z., Kotaki, M., Inai, R., Ramakrishna, S. (2005) Tissue Eng. 11: pp. 101 CrossRef
11. Huang, W., Li, X., Xue, Y., Huang, R., Deng, H., Ma, Z. (2013) Int. J. Biol. Macromol. 53: pp. 26 CrossRef
12. Wang, X., Ding, B., Sun, G., Wang, M., Yu, J. (2013) Prog. Mater. Sci. 58: pp. 1173 CrossRef
13. Deng, H., Zhou, X., Wang, X., Zhang, C., Ding, B., Zhang, Q., Du, Y. (2010) Carbohydr. Polym. 80: pp. 474 CrossRef
14. Goh, Y.-F., Shakir, I., Hussain, R. (2013) J. Mater. Sci. 48: pp. 3027 CrossRef
15. Liao, S., Murugan, R., Chan, C. K., Ramakrishna, S. (2008) J. Mech. Behav. Biomed. Mater. 1: pp. 252 CrossRef
16. Chaplin, R. P., Lee, A. J., Hooper, R. M., Clarke, M. (2006) J. Mater. Sci.-Mater. Med. 17: pp. 1433 CrossRef
17. Dong, H., Nyame, V., MacDiarmid, A. G., Jones, W. E. (2004) J. Polym. Sci. Part B: Polym. Phys. 42: pp. 3934 CrossRef
18. Mousa, W. F., Kobayashi, M., Shinzato, S., Kamimura, M., Neo, M., Yoshihara, S., Nakamura, T. (2000) Biomaterials 21: pp. 2137 CrossRef
19. Wu, C., Ramaswamy, Y., Zhu, Y., Zheng, R., Appleyard, R., Howard, A., Zreiqat, H. (2009) Biomaterials 30: pp. 2199 CrossRef
20. Yuan, J., Shen, J., Kang, I. K. (2008) Polym. Int. 57: pp. 1188 CrossRef
21. Fratzl, P., Gupta, H. S., Paschalis, E. P., Roschger, P. (2004) J. Mater. Chem. 14: pp. 2115 CrossRef
22. Yuan, H., Li, Y., Bruijn, J., Groot, K., Zhang, X. (2000) Biomaterials 21: pp. 1283 CrossRef
23. Kilpadi, K. L., Chang, P. L., Bellis, S. L. (2001) J. Biomed. Mater. Res. Part B 57: pp. 258 CrossRef
24. Nirmala, R., Nam, K. T., Park, D. K., Baek, W., Navamathavan, R., Kim, H. Y. (2010) Surf. Coat. Technol. 205: pp. 174 CrossRef
25. Du, C., Cui, F. Z., Zhu, X. D., Groot, K. (1999) J. Biomed. Mater. Res. Part B 44: pp. 407 CrossRef
26. Kim, H.-W., Knowles, J. C., Kim, H.-E. (2004) Biomaterials 25: pp. 1279 CrossRef
27. Thomas, V., Dean, D. R., Jose, M. V., Mathew, B., Chowdhury, S., Vohra, Y. K. (2007) Biomacromolecules 8: pp. 631 CrossRef
28. Fischer, R. L., McCoy, M. G., Grant, S. A. (2012) J. Mater. Sci. Mater. Med. 23: pp. 1645 CrossRef
29. Kane, R. J., Roeder, R. K. (2012) J. Mech. Behav. Biomed. Mater. 7: pp. 41 CrossRef
30. Antunes, J. C., Oliveira, J. M., Reis, R. L., Soria, J. M., Gomez-Ribelles, J. L., Mano, J. F. (2010) J. Biomed. Mater. Res. Part A 94: pp. 856
31. Liu, H., Zhang, L., Shi, P., Zou, Q., Zuo, Y., Li, Y. (2010) J. Biomed. Mater. Res. Part B 95: pp. 36 CrossRef
32. Deng, H., Li, X., Ding, B., Du, Y., Li, G., Yang, J., Hu, X. (2011) Carbohydr. Polym. 83: pp. 973 CrossRef
33. Li, W., Li, X., Li, W., Wang, T., Li, X., Pan, S., Deng, H. (2012) Eur. Polym. J. 48: pp. 1846 CrossRef
34. Rabadjieva, D., Tepavitcharova, S., Sezanova, K., Gergulova, R., Titorenkova, R., Petrov, O., Dyulgerova, E. (2011) Nanosci. Nanotechnol. 11: pp. 182 CrossRef
35. Zhang, H. (2011) J. Bioact. Compat. Polym. 26: pp. 590 CrossRef
36. Hou, X., Yin, G., Chen, X., Liao, X., Yao, Y., Huang, Z. (2011) Appl. Surf. Sci. 257: pp. 3417 CrossRef
37. Deng, H., Wang, X., Liu, P., Ding, B., Du, Y., Li, G., Hu, X., Yang, J. (2011) Carbohydr. Polym. 83: pp. 239 CrossRef
38. Nagarwal, R. C., Kumar, R., Dhanawat, M., Pandit, J. K. (2011) Colloid Surf. B-Biointerfaces 86: pp. 28 CrossRef
39. Cao, H., Chen, X., Yao, J., Shao, Z. (2012) J. Mater. Sci. 48: pp. 150 CrossRef
40. Wu, C., Chang, J., Ni, S., Wang, J. (2006) J. Biomed. Mater. Res. Part A 76: pp. 73 CrossRef
41. Wu, C., Chang, J., Zhai, W., Ni, S., Wang, J. (2006) J. Biomed. Mater. Res. Part B 78: pp. 47 CrossRef
42. Mao, L., Shen, L., Niu, J., Zhang, J., Ding, W., Wu, Y., Fan, R., Yuan, G. (2013) Nanoscale 5: pp. 9517 CrossRef
43. Kai, D., Prabhakaran, M. P., Jin, G., Ramakrishna, S. (2011) J. Biomed. Mater. Res. Part A 99: pp. 376 CrossRef
44. Liu, H., Wang, S., Qi, N. (2012) J. Appl. Polym. Sci. 125: pp. E468 CrossRef
45. Chang, B.-W., Chen, C.-H., Ding, S.-J., Chen, D. C.-H., Chang, H.-C. (2005) Sens. Actuators B-Chem. 105: pp. 159 CrossRef
46. Pelipenko, J., Kocbek, P., Govedarica, B., Ro拧ic, R., Baumgartner, S., Kristl, J. (2012) Eur. J. Pharm. Biopharm. 84: pp. 401 CrossRef - 刊物类别：Chemistry and Materials Science
- 刊物主题：Chemistry
Polymer Sciences - 出版者：The Korean Fiber Society
- ISSN：1875-0052
文摘
Bone tissue engineering has great potential but requires an appropriate substrate with good bioactivity. In this study, poly(lactic acid) (PLA)/poly(methyl methacrylate) (PMMA)/nano-hydroxyapatite (n-HA) hybrid nanofibrous scaffolds were fabricated via electrospinning. The morphologies of the scaffolds were observed by scanning electron microscopy, transmission electron microscopy and the structures of the scaffolds were measured by fourier transform infrared spectrum. After immersion in simulated body fluid, the more deposition of ball-like apatite can be observed on the surface of the hybrid PLA/PMMA/n-HA scaffold. In vitro degradation experiments showed that the less degradation occurred in the hybrid PLA/PMMA/n-HA scaffold. The studies of cell adhesion and growth capability were investigated by incubating the osteoblast-like cells (MG-63) in the scaffolds, which verified the addition of n-HA could promote the adhesion and proliferation of the Human osteoblast-like cells (MG-63). Hence, the electrospun hybrid PLA/PMMA/n-HA nanofibrous scaffold is a promising biomaterial, propitious to be a substrate for bone tissue engineering.