Expression of genes involved in the T cell signalling pathway in circulating immune cells of cattle 24 months following oral challenge with Bovine Amyloidotic Spongiform Encephalopathy (BASE)
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- 作者：Andrea Trovato ; Simona Panelli ; Francesco Strozzi…
- 关键词：Bovine Amyloidotic Spongiform Encephalopathy (BASE) ; Transmissible Spongiform Encephalopathies (TSEs) ; Immune function ; Cattle
- 刊名：BMC Veterinary Research
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：11
- 期：1
- 全文大小：601 KB
- 刊物主题：Veterinary Medicine; Zoology; Transgenics;
- 出版者：BioMed Central
- ISSN：1746-6148
文摘
Background Bovine Amyloidotic Spongiform Encephalopathy (BASE) is a variant of classical BSE that affects cows and can be transmitted to primates and mice. BASE is biochemically different from BSE and shares some molecular and histo-pathological features with the MV2 sub-type of human sporadic Creutzfeld Jakob Disease (sCJD).