AgF-Mediated Fluorinative Homocoupling of gem-Difluoroalkenes

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• 作者：Bing Gao ; Yanchuan Zhao ; Chuanfa Ni ; Jinbo Hu
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：January 3, 2014
• 年：2014
• 卷：16
• 期：1
• 页码：102-105
• 全文大小：311K
• ISSN：1523-7052

文摘

A novel silver(I)-fluoride-mediated homocoupling reaction of 尾,尾-difluorostyrene derivatives is described. The transformation is initiated via nucleophilic addition of silver(I) fluoride to 尾,尾-difluorostyrenes, which is followed by dimerization of the corresponding benzylsilver intermediates. The reaction shows good substrate scope, functional group tolerance, and represents the first report on the reactivity of (伪-trifluoromethyl)benzylsilver species.