Total Synthesis of the Terpenoid Buddledone A: 11-Membered Ring-Closing Metathesis

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• 作者：Zhengxin Cai ; Nattawut Yongpruksa ; Michael Harmata
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：April 6, 2012
• 年：2012
• 卷：14
• 期：7
• 页码：1661-1663
• 全文大小：206K
• 年卷期：v.14,no.7(April 6, 2012)
• ISSN：1523-7052

文摘

The first total synthesis of buddledone A was accomplished in seven steps from methyl ethyl ketone (MEK). The key step in the sequence featured an 11-membered ring formation by ring-closing metathesis.