Total Synthesis of (卤)-Cephalosol
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- 作者：Yuanzhen Xie ; Ning Wang ; Bin Cheng ; Hongbin Zhai
- 刊名：Organic Letters
- 出版年：2012
- 出版时间：January 6, 2012
- 年：2012
- 卷：14
- 期：1
- 页码：3-5
- 全文大小：687K
- 年卷期：v.14,no.1(January 6, 2012)
- ISSN：1523-7052
文摘
A concise and efficient total synthesis of (卤)-cephalosol has been completed (5 steps from known ester 5, 39% overall yield), featuring a Cu(II)-promoted haloisocoumarin formation and sequential Suzuki cross-coupling/intramolecular oxo-Michael addition.