Room-Temperature Ligand-Free Pd/C-Catalyzed C鈥揝 Bond Formation: Synthesis of 2-Substituted Benzothiazoles

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• 作者：Yannan Cheng ; Qian Peng ; Weigang Fan ; Pixu Li
• 刊名：Journal of Organic Chemistry
• 出版年：2014
• 出版时间：June 20, 2014
• 年：2014
• 卷：79
• 期：12
• 页码：5812-5819
• 全文大小：377K
• 年卷期：v.79,no.12(June 20, 2014)
• ISSN：1520-6904

文摘

The synthesis of 2-substituted benzothiazoles has been achieved via cyclization of o-iodothiobenzanilide derivatives using Pd/C as the catalyst at room temperature. The protocol is ligand-free, additive-free, and high-yielding and involves very mild conditions.