Synthesis of α-Chloroaldoxime O-Methanesulfonates and Their Use in the Synthesis of Functionalized Benzimidazoles

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• 作者：Yuhei Yamamoto ; Hiroo Mizuno ; Takayuki Tsuritani ; Toshiaki Mase
• 刊名：Journal of Organic Chemistry
• 出版年：2009
• 出版时间：February 6, 2009
• 年：2009
• 卷：74
• 期：3
• 页码：1394-1396
• 全文大小：131K
• 年卷期：v.74,no.3(February 6, 2009)
• ISSN：1520-6904

文摘

Three different α-chloroaldoxime O-methanesulfonates were synthesized to investigate their chemical properties. The compounds were found to be stable and were able to be stored at ambient temperature without any precautions. The reactions with anilines were investigated, and it was found that an additive is required to activate the sulfonate. TMEDA was found to be the most efficient additive, and various benzimidazoles were synthesized through the reaction.