Copper-Catalyzed Aerobic Oxidative Coupling of Aromatic Alcohols and Acetonitrile to β-Ketonitriles
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- 作者：Jiaxuan Shen ; Dejun Yang ; Yuxiao Liu ; Shuangshuang Qin ; Jingwu Zhang ; Jiangkai Sun ; Chunhui Liu ; Chaoyang Liu ; Xiaomei Zhao ; Changhu Chu ; Renhua Liu
- 刊名：Organic Letters
- 出版年：2014
- 出版时间：January 17, 2014
- 年：2014
- 卷：16
- 期：2
- 页码：350-353
- 全文大小：249K
- ISSN：1523-7052
文摘
A practical, convenient, and cheap copper-catalyzed aerobic oxidative coupling of aromatic alcohols and acetonitrile to 尾-ketonitriles has been developed. The green C鈥揅 bond formation involving the loss of two hydrogen atoms from the corresponding two carbons, respectively, unlocks opportunities for markedly different synthetic strategies.