SmI2-Mediated Carbon−Carbon Bond Fragmentation in α-Aminomethyl Malonates

详细信息    查看全文

• 作者：Qiongfeng Xu ; Bin Cheng ; Xinshan Ye ; Hongbin Zhai
• 刊名：Organic Letters
• 出版年：2009
• 出版时间：September 17, 2009
• 年：2009
• 卷：11
• 期：18
• 页码：4136-4138
• 全文大小：132K
• 年卷期：v.11,no.18(September 17, 2009)
• ISSN：1523-7052

文摘

A new and efficient samarium diiodide-promoted carbon−carbon bond fragmentation reaction of α-aminomethyl malonates, taking place normally at room temperature and generating the corresponding deaminomethylation products in 74−94% yields, is reported. The presence of the amino group is necessary for the success of the current transformation.