Synthesis of Phosphaisocoumarins through Rhodium-Catalyzed Cyclization Using Alkynes and Arylphosphonic Acid Monoesters

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• 作者：Jungmin Seo ; Youngchul Park ; Incheol Jeon ; Taekyu Ryu ; Sangjune Park ; Phil Ho Lee
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：July 5, 2013
• 年：2013
• 卷：15
• 期：13
• 页码：3358-3361
• 全文大小：314K
• 年卷期：v.15,no.13(July 5, 2013)
• ISSN：1523-7052

文摘

A rhodium-catalyzed cyclization using alkynes and arylphosphonic acid monoesters for the synthesis of phosphaisocoumarins is reported. A number of arylphosphonic acid monoesters were selectively cyclized in high yields with functional group tolerance. In addition, unsymmetrical alkynes are applied in high regioselectivity.