Directly Fused Highly Substituted Naphthalenes via Pd-Catalyzed Dehydrogenative Annulation of N,N-Dimethylaminomethyl Ferrocene Using a Redox Process with a Substrate

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• 作者：Hao Zhang ; Xiuling Cui ; Xiangna Yao ; Hui Wang ; Jianye Zhang ; Yangjie Wu
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：June 15, 2012
• 年：2012
• 卷：14
• 期：12
• 页码：3012-3015
• 全文大小：336K
• 年卷期：v.14,no.12(June 15, 2012)
• ISSN：1523-7052

文摘

N,N-Dimethylaminomethyl ferrocenium could be generated in situ and served as a terminal oxidant for Pd-catalyzed directly dehydrogenative annulations of N,N-dimethylaminomethyl ferrocene and internal alkynes. This procedure utilized the redox activity of ferrocene and avoided adding an oxidant. A series of highly arylated naphthalenes functionalized by ferrocene were obtained in 53鈥?1% yields.