In Vivo Antioxidant Activities of Essential Oils and Their Constituents from Leaves of the Taiwanese Cinnamomum osmophloeum
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- 作者：Fu-Lan Hsu ; Wen-Hsuan Li ; Chan-Wei Yu ; Yi-Chen Hsieh ; Ying-Fei Yang ; Jui-Tung Liu ; Justin Shih ; Yu-Ju Chu ; Pei-Ling Yen ; Shang-Tzen Chang ; Vivian Hsiu-Chuan Liao
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2012
- 出版时间：March 28, 2012
- 年：2012
- 卷：60
- 期：12
- 页码：3092-3097
- 全文大小：279K
- 年卷期：v.60,no.12(March 28, 2012)
- ISSN：1520-5118
文摘
Cinnamomum osmophloeum Kaneh is an indigenous tree species in Taiwan. In this study, phytochemical characteristics and antioxidant activities of the essential oils and key constituents from the leaves of two C. osmophloeum clones were investigated. The two trees possess two chemotypes, which were classified as the cinnamaldehyde type and camphor type. We demonstrated that the essential oils from C. osmophloeum leaves exerted in vivo antioxidant activities in Caenorhabditis elegans. In addition, trans-cinnamaldehyde and d-(+)-camphor, which respectively represent the major compounds in the cinnamaldehyde-type and camphor-type trees, exerted significant in vivo antioxidant activities against juglone-induced oxidative stress in C. elegans. Moreover, expressions of antioxidative-related genes, including superoxide dismutase (SOD) and glutathione S-transferase (GST), were significantly induced by trans-cinnamaldehyde and d-(+)-camphor from C. osmophloeum leaves. Our results showed that the essential oils from C. osmophloeum leaves and their major compounds might have good potential for further development as nutraceuticals or antioxidant remedies.