Ammonium Iodide Induced Nonradical Regioselective Sulfenylation of Flavones via a C鈥揌 Functionalization Process

详细信息    查看全文

• 作者：Wannian Zhao ; Ping Xie ; Zhaogang Bian ; Aihua Zhou ; Haibo Ge ; Min Zhang ; Yingcai Ding ; Lian Zheng
• 刊名：Journal of Organic Chemistry
• 出版年：2015
• 出版时间：September 18, 2015
• 年：2015
• 卷：80
• 期：18
• 页码：9167-9175
• 全文大小：551K
• ISSN：1520-6904

文摘

A novel and highly regioselective ammonium iodide-induced nonradical sulfenylation method for the construction of a C鈥揝 bond was developed via C鈥揌 functionalization. With DMSO or R¹SO₂NHNH₂ as a sulfenylating agent, MeS- and R¹S-substituted flavone derivatives were obtained in good yields. This method enriches current C鈥揝 bond formation chemistry, making it a highly valuable and practical method in pharmaceutical industry.