Expanding Stereochemical and Skeletal Diversity Using Petasis Reactions and 1,3-Dipolar Cycloadditions
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- 作者：Giovanni Muncipinto ; Taner Kaya ; J. Anthony Wilson ; Naoya Kumagai ; Paul A. Clemons ; Stuart L. Schreiber
- 刊名：Organic Letters
- 出版年：2010
- 出版时间：November 19, 2010
- 年：2010
- 卷：12
- 期：22
- 页码：5230-5233
- 全文大小：249K
- 年卷期：v.12,no.22(November 19, 2010)
- ISSN：1523-7052
文摘
A short and modular synthetic pathway using intramolecular 1,3-dipolar cycloaddition reactions and yielding functionalized isoxazoles, isoxazolines, and isoxazolidines is described. The change in shape of previous compounds and those in this study is quantified and compared using principal moment-of-inertia shape analysis.