Surface Area of Carbon Nanoparticles: A Dose Metric for a More Realistic Ecotoxicological Assessment

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• 作者：Antoine Mottier ; Florence Mouchet ; Christophe Laplanche ; Stéphanie Cadarsi ; Laura Lagier ; Jean-Charles Arnault ; Hugues A. Girard ; Verónica León ; Ester Vázquez ; Cyril Sarrieu ; Éric Pinelli ; Laury Gauthier ; Emmanuel Flahaut
• 刊名：Nano Letters
• 出版年：2016
• 出版时间：June 8, 2016
• 年：2016
• 卷：16
• 期：6
• 页码：3514-3518
• 全文大小：317K
• 年卷期：0
• ISSN：1530-6992

文摘

Engineered nanoparticles such as graphenes, nanodiamonds, and carbon nanotubes correspond to different allotropes of carbon and are among the best candidates for applications in fast-growing nanotechnology. It is thus likely that they may get into the environment at each step of their life cycle: production, use, and disposal. The aquatic compartment concentrates pollutants and is expected to be especially impacted. The toxicity of a compound is conventionally evaluated using mass concentration as a quantitative measure of exposure. However, several studies have highlighted that such a metric is not the best descriptor at the nanoscale. Here we compare the inhibition of Xenopus laevis larvae growth after in vivo exposure to different carbon nanoparticles for 12 days using different dose metrics and clearly show that surface area is the most relevant descriptor of toxicity for different types of carbon allotropes.