Synthesis of Fluorinated and Nonfluorinated Tebufenpyrad Analogues for the Study of Anti-angiogenesis MOA
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- 作者：Raquel Rom谩n ; Antonio Navarro ; Dariusz Wodka ; Maria Alvim-Gaston ; Saba Husain ; Natalie Franklin ; Antonio Sim贸n-Fuentes ; Santos Fustero
- 刊名：Organic Process Research & Development
- 出版年：2014
- 出版时间：August 15, 2014
- 年：2014
- 卷：18
- 期：8
- 页码：1027-1036
- 全文大小：535K
- ISSN：1520-586X
文摘
In this contribution we report the synthesis of fluorinated and nonfluorinated tebufenpyrad analogues to explore potential druglike properties through the phenotypic screening as part of the Lilly Open Innovation Drug Discovery (OIDD) program.