Two pairs of new benzofuran enantiomers with unusual skeletons from Eupatorium chinense

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• 作者：Wen-Jing Wang^a ; ^b ; Lei Wang^a ; ^b ; ^{cpuwanglei@126.com} ; Xiao-Jun Huang^a ; ^b ; Ren-Wang Jiang^a ; Xiao-Lin Yang^a ; ^b ; Dong-Mei Zhang^a ; ^b ; Wei-Min Chen^a ; Ben-Qin Tang^a ; ^b ; Ying Wang^a ; ^b ; Xiao-Qi Zhang^a ; ^b ; ^{xqzhang74@hotmail.com} ; Wen-Cai Ye^a ; ^b ; ^{chywc@yahoo.com.cn}
• 关键词：Benzofuran ; Eupatorium chinense ; Compositae
• 刊名：Tetrahedron Letters
• 出版年：2013
• 出版时间：26 June, 2013
• 年：2013
• 卷：54
• 期：26
• 页码：3321-3324
• 全文大小：702 K

文摘

Two pairs of new enantiomeric benzofurans with unusual skeletons, (+)- and (?)-eupachinin A (1), as well as (+)- and (?)-eupachinin B (2), were isolated from the roots of Eupatorium chinense by chiral HPLC. Their structures with absolute configurations were elucidated on the basis of spectroscopic methods, X-ray diffraction analysis, and quantum chemical calculation. The plausible biogenetic pathway of 1 and 2 was also proposed.