Injectable alginate/hydroxyapatite gel scaffold combined with gelatin microspheres for drug delivery and bone tissue engineering
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- 作者：Jingxuan Yana ; Yuting Miaoa ; Huaping Tana ; hptan@njust.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Tianle Zhoua ; Zhonghua Lingb ; Yong Chenb ; 13813889089@139.com" class="auth_mail" title="E-mail the corresponding author ; Xiaodong Xingc ; Xiaohong Hud
- 关键词：Hydrogels ; Alginate ; Hydroxyapatite ; Microspheres ; Drug delivery ; Tissue engineering
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 June 2016
- 年：2016
- 卷：63
- 期：Complete
- 页码：274-284
- 全文大小：4827 K
文摘
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Ionically and slowly cross-linked alginate-based gel scaffolds were fabricated.
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Hydroxyapatite and gelatin microspheres successfully improved the gel network.
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Tetracycline hydrochloride in the gel scaffold was released in a controlled fashion.