Oleanane-type triterpenoid saponins from Xanthoceras sorbifolia Bunge

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• 作者：Lili Yu^a ; ^b ; ^c ; Xiaolong Tang^a ; ^b ; Lixia Chen^a ; ^b ; Miaomiao Wang^d ; Junfeng Jian^d ; Shijie Cao^d ; Xiaobing Wang^d ; Ning Kang^d ; ^{kangndd@163.com} ; Feng Qiu^a ; ^b ; ^{fengqiu20070118@163.com}
• 关键词：Xanthoceras sorbifolia ; Triterpenoid saponin ; Sorbifoliaside ; Antitumor activity
• 刊名：Fitoterapia
• 出版年：2012
• 出版时间：December, 2012
• 年：2012
• 卷：83
• 期：8
• 页码：1636-1642
• 全文大小：359 K

文摘

Phytochemical analysis of the extract from the seed oil leavings of Xanthoceras sorbifolia Bunge led to the isolation of five new oleanane-type triterpeniod saponins, sorbifoliasides G-K (1-5). Their structures were elucidated on the basis of spectroscopic analysis and chemical derivatization. To our knowledge, compound 5 is the first example of a naturally occurring 3,28-O-bisdesmosic triterpenoid saponin with olefinic linkages at C12 and C15. The cytotoxicity of all compounds against ten selected human cancer cell lines was assayed.