Isolated paediatric neurosarcoidosis presenting as epilepsia partialis continua: A case report and review of literature

详细信息    查看全文

• 作者：Geetha An ; Fang En Sin ; Elizabeth Soilleux ; Julie Ch ; ra ; Katharine Piddington ; Gerardine Quaghebeur ; Nick Wilkinson ; Zenobia Zaiwalla ; Robin Kennett ; Tony McShane
• 关键词：Epilepsia partialis continua ; Neurosarcoidosis ; Child
• 刊名：European Journal of Paediatric Neurology
• 出版年：2013
• 出版时间：September, 2013
• 年：2013
• 卷：17
• 期：5
• 页码：429-436
• 全文大小：2042 K

文摘

Isolated paediatric neurosarcoidosis (IPN) is exceptionally rare and only seven cases have been reported so far in the literature. We report the clinical and radiological profile of a 7 year-old boy with epilepsia partialis continua (EPC) who was initially thought to have Acute Disseminated Encephalomyelitis (ADEM), but was subsequently found to have isolated neurosarcoidosis. Additionally, we performed a literature search on Medline and Embase and secondary sources of data such as reference list of articles reviewed. Whilst cranial neuropathy is the commonest presenting feature in adults with neurosarcoidosis, paediatric patients are more likely to present with seizures. Diagnosis presents a clinical challenge as a result of its protean manifestations. Due to its rarity, there remains a lack of evidence base to inform the best choice of treatment for these children. Our patient was successfully treated with a combination of various immunomodulants.