Sodium sulfite promotes the assembly and secretion of very low-density lipoprotein in HL-7702 hepatocytes
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- 作者：Jianying Bai ; jybai66@aliyun.com ; Peiyu Lei ; Chunyan Zhao ; Youping Wang ; Dandan Yan ; Shuyun Yang
- 关键词：TG ; triglyceride ; VLDL ; very low-density lipoprotein ; apoB100 ; apolipoprotein B100 ; ELISA ; enzyme-linked immunosorbent assay ; CPT1 ; carnitine palmitoyl transferase 1 ; SREBP1 ; sterol regulatory element binding protein-1 ; MTP ; microsomal triglyceride transfer protein ; TGH ; triglyceride hydrolase ; Arf1 ; ADP-ribosylation factor-1 ; COP I ; coated protein I ; LDLR ; low-density lipoprotein receptor ; NAFLD ; Nonalcoholic fatty liver disease
- 刊名：Toxicology Reports
- 出版年：2016
- 出版时间：2016
- 年：2016
- 卷：3
- 期：Complete
- 页码：98-104
- 全文大小：1542 K
- 卷排序：3
文摘
Na2SO3 can increase the secretion of VLDL and apoB100 of human hepatocytes. Na2SO3 can increase the expression of MTP and TGH in human hepatocytes. Na2SO3 can not increase TG levels inside the human hepatocytes, but can increase the extracellular TG level.