Population-based prevalence survey.
Presenting and pinhole visual acuity were tested using picture optotypes or, in children with pinhole vision < 6/18, a Snellen tumbling E chart. Comprehensive eye examinations and cycloplegic refraction were carried out for children with pinhole vision < 6/18 in the better-seeing eye.
All examinations were completed on 17,699 children aged 3 to 6 years (95.3 % of sample). Subjects with bilateral correctable low vision (presenting vision < 6/18 correctable to ≥ 6/18) numbered 57 (0.322 % ; 95 % confidence interval [CI], 0.237 % to 0.403 % ), while 14 (0.079 % ; 95 % CI, 0.038 % to 0.120 % ) had bilateral uncorrectable low vision (best-corrected vision of < 6/18 and ≥ 3/60), and 5 subjects (0.028 % ; 95 % CI, 0.004 % to 0.054 % ) were bilaterally blind (best-corrected acuity < 3/60). The etiology of 76 cases of visual impairment included: refractive error in 57 children (75 % ), hereditary factors (microphthalmos, congenital cataract, congenital motor nystagmus, albinism, and optic nerve disease) in 13 children (17.1 % ), amblyopia in 3 children (3.95 % ), and cortical blindness in 1 child (1.3 % ). The cause of visual impairment could not be established in 2 (2.63 % ) children. The prevalence of visual impairment did not differ by gender, but correctable low vision was significantly (P < .0001) more common among urban as compared with rural children.
The leading causes of visual impairment among Chinese preschool-aged children are refractive error and hereditary eye diseases. A higher prevalence of refractive error is already present among urban as compared with rural children in this preschool population.