Parenchymal density changes in acute pulmonary embolism: Can quantitative CT be a diagnostic tool? A preliminary study

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• 作者：Ikram Eda Duman^a ; ^{edda_ikram@hotmail.com} ; Canan Cimsit^a ; ^{canancimsit@gmail.com} ; Sehnaz Olgun Yildizeli^b ; ^{drsehnazolgun@yahoo.com} ; Nuri Cagatay Cimsit^a ; ^{cagataycimsit@gmail.com}
• 关键词：QCT ; Quantitative CT ; PE ; Pulmonary embolism ; CTPA ; CT pulmonary angiography ; MLD ; Mean lung density ; PDV ; Percentage distribution values ; LMPA ; Left main pulmonary artery ; RMPA ; Right main pulmonary artery ; RLLB ; Right lower lobe branch ; RLSB ; Right lower segment branch ; RMLB ; Right middle lobe branch ; RMSB ; Right middle segment branch ; RULB ; Right upper lobe branch ; RUSB ; Right upper segment branch ; LLLB ; Left lower lobe branch ; LLSB ; Left lower segment branch ; LLB ; Left lingular lobe branch
• 刊名：Clinical Imaging
• 出版年：2017
• 出版时间：January-February 2017
• 年：2017
• 卷：41
• 期：Complete
• 页码：157-163
• 全文大小：1171 K
• 卷排序：41

文摘

Determine the ability of quantitative CT (QCT) in defining parenchymal density changes in acute pulmonary embolism (PE).Material & methodsMean lung density (MLD) and percentage distribution values (PDV) were calculated in 34 patients suspected of PE using software application based on computerized volumetric anatomical segmentation.ResultsTotal, left, and right MLD differed significantly between emboli positive(n = 23) and negative(n = 11) groups(p < 0.006, p < 0.009, p < 0.014). PDVs differed between groups (p < 0.05) except for LUZ and RLZ. When PE was present in lobe &/segment branches, PDVs were significantly lower except RUZ.ConclusionQCT is a promising application for defining parenchymal density changes in PE revealing potential functional impact of emboli. This preliminary study suggests QCT could provide added value to CTPA in peripheral PE.