Alendronate conjugated nanoparticles for calcification targeting
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- 作者：Nanying Lia ; b ; Juqing Songa ; b ; Guanglin Zhua ; b ; Xuetao Shib ; mrshixuetao@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Yingjun Wanga ; imwangyj@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Poly(lactic-co-glycolic acid) ; Nanoparticle ; Dopamine ; Calcification-targeting
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 June 2016
- 年：2016
- 卷：142
- 期：Complete
- 页码：344-350
- 全文大小：2761 K
文摘
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The synthesis of a novel calcification-targeting nanoparticle (NP) is reported.
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NPs can pass through obstructive hydrogel (mimicking soft tissues).
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NPs can directly bind themselves to hydroxyapatite (HA) NPs (mimicking calcified spots).
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NPs can directly bind themselves to HA porous scaffolds (mimicking calcified tissues).