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Ammonia promotes endothelial cell survival via the heme oxygenase-1-mediated release of carbon monoxide
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文摘
Ammonia stimulates HO-1 expression in endothelial cells via the ROS-Nrf2 pathway. Glutamine induces HO-1 expression in endothelial cells via the formation of ammonia. Ammonia enhances endothelial cell viability via the HO-1-mediated release of CO. Ammonia is an important signaling gas that promotes endothelial cell survival.

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