Lemon balm extract (Melissa officinalis, L.) promotes melanogenesis and prevents UVB-induced oxidative stress and DNA damage in a skin cell model
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- 作者：Almudena Pé ; rez-Sá ; ncheza ; 1 ; Enrique Barrajó ; n-Catalá ; na ; b ; 1 ; Marí ; a Herranz-Ló ; peza ; Juliá ; n Castilloc ; d ; 2 ; Vicente Micola ; e ; vmicol@umh.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：6-4PPs ; pyrimidine (6-4) pyrimidone ; CPDs ; cyclobutane pyrimidine dimers ; DDR ; DNA damage response ; DMSO ; dimethyl sulfoxide ; DSBs ; double-strand brakes ; H2DCF-DA ; 2&prime ; 7&prime ; -dichlorofluorescein diacetate ; HNE ; 4-hydroxy-2-nonenal ; IBMX ; 3-isobutyl-1-methylxanthine ; LBE ; lemon balm extract ; MDA ; malondialdehyde ; ORAC ; oxygen radical absorbance capacity ; PBS ; phosphate-buffered saline ; RA ; rosmarinic acid ; ROS ; reactive oxygen species ; SSBs ; single-strand brakes ; TEAC ; trolox equivalent an
- 刊名：Journal of Dermatological Science
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：84
- 期：2
- 页码：169-177
- 全文大小：1425 K
文摘
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Lemon balm extract contains rosmarinic and salvianolic acids as the main polyphenols.
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10">LBE protects skin cells against UVB-induced cytotoxicity and ROS generation.
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15">LBE decreases UVB-induced DNA damage and the DNA damage response in keratinocytes.
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Lemon balm extract promotes melanogenesis in melanoma cells.
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LBE has the potential to protect human skin against UV-induced damage.
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