Gastroprotective effects of hydroethanolic root extract of Arrabidaea brachypoda: Evidences of cytoprotection and isolation of unusual glycosylated polyphenols

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• 作者：Claudia Quintino da Rocha^a ; ^b ; Felipe Meira de-Faria^c ; ^d ; Laurence Marcourt^b ; Samad Nejad Ebrahimi^e ; Bruna Tiemi Kitano^d ; Amanda Franceschini Ghilardi^d ; Anderson Luiz Ferreira^d ; ^f ; Ana Cristina Alves de Almeida^d ; Ricardo José ; Dunder^c ; Alba Regina Monteiro Souza-Brito^c ; ^d ; Matthias Hamburger^g ; Wagner Vilegas^a ; ^{vilegasw@gmail.com} ; Emerson Ferreira Queiroz^b ; ^{emerson.ferreira@unige.ch} ; Jean-Luc Wolfender^b
• 关键词：Arrabidaea brachypoda ; Bignoniaceae ; Gastric ulcer ; Gastroprotective effect ; In vivo assays ; Glycosylated dimeric flavonoids
• 刊名：Phytochemistry
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：135
• 期：Complete
• 页码：93-105
• 全文大小：1482 K
• 卷排序：135

文摘

The EtOH root extract shows significant in vivo gastroprotective effects. HPLC-MS profile of the extract revealed the presence of unusual molecular formulas. Targeted isolation afforded seven unusual glycosylated dimeric flavonoids.