The Journey of the Autophagosome through Mammalian Cell Organelles and Membranes
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- 作者：Diana Molino ; Naï ; ma Zemirli ; Patrice Codogno ; Etienne Morel ; etienne.morel@inserm.fr
- 关键词：ER ; endoplasmic reticulum ; ATG ; autophagy-related gene ; mTORC1 ; mammalian target of rapamycin complex 1 ; PI3KC3 ; class III PI3 kinase ; PI3P ; phosphatidyl-inositol-3-phosphate ; COPs ; coating proteins ; SNAREs ; small Rab GTPases ; membrane fusion proteins ; MAMs ; mitochondria-associated membranes ; ERGIC ; ER-to-Golgi intermediate compartment ; TGN ; trans-Golgi network ; PM ; plasma membrane ; LAP ; LC3-associated phagocytosis ; TSC ; tuberous sclerosis complex ; ROS ; reactive oxygen species ; ERS ; ER stress ; T
- 刊名：Journal of Molecular Biology
- 出版年：2017
- 出版时间：17 February 2017
- 年：2017
- 卷：429
- 期：4
- 页码：497-514
- 全文大小：1013 K
- 卷排序：429
文摘
Autophagosome are formed from at ER membrane sites supplied with other endo-membranes. Autophagosome are tightly connected with trafficking machineries and pathways in the cell. Autophagy induction and regulation are often dependant on endo-membranes signaling machineries.